J Korean Surg Soc.  2001 Dec;61(6):614-618.

Mesenteric Infarction of the Systemic Lupus Erythematosus and Antiphospholipid Syndrome Patient

Affiliations
  • 1Department of General Surgery, Ewha Womans University College of Medicine, Seoul, Korea. ywkimmed@mm.ewha.ac.kr

Abstract

Antiphospholipid syndrome is characterized by arterial or venous thrombosis and the production of antiphospholipid antibodies. Antiphospholipid syndrome may present primarily or secondary to systemic lupus erythematosus. The clinical features include multiple thrombosis, cerebral diseases, abortion in female, thrombocytopenia and so on. The treatment is based on anticoagulants, steroids, immunosuppressive agents and antiplatelet drugs. We report a case of a 29- year-old man who was admitted to Ewha Womans University Mok-dong Hospital with a generalized peritonitis. On emergency exploratory laparotomy, segmental infarction of the terminal ileum and the right colon was revealed and a right colon and ileal resection was performed. During the postoperative period, the patient was finally diagnosed having antiphospholipid syndrome with systemic lupus erythematosus. He also had ischemic heart disease due to coronary artery thrombosis and pulmonary embolism due to deep vein thrombosis of the lower extremities. He eventually expired following a restorative ileocolostomy owing to anastomotic leakage and sepsis.

Keyword

Mesenteric infarction; Systemic lupus erythematosus; Antiphospholipid syndrome

MeSH Terms

Anastomotic Leak
Antibodies, Antiphospholipid
Anticoagulants
Antiphospholipid Syndrome*
Colon
Coronary Vessels
Emergencies
Female
Humans
Ileum
Immunosuppressive Agents
Infarction*
Intracranial Thrombosis
Laparotomy
Lower Extremity
Lupus Erythematosus, Systemic*
Myocardial Ischemia
Peritonitis
Platelet Aggregation Inhibitors
Postoperative Period
Pulmonary Embolism
Sepsis
Steroids
Thrombocytopenia
Thrombosis
Venous Thrombosis
Antibodies, Antiphospholipid
Anticoagulants
Immunosuppressive Agents
Platelet Aggregation Inhibitors
Steroids
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