Korean J Gastroenterol.  1999 Aug;34(2):143-150.

Influence of Helicobacter pylori Infection on Proximal Gastric Motor Function in Functional Dyspepsia

Abstract

BACKGROUND/AIMS: Little is known about the effect of Helicobacter pylori (HP) infection on proximal gastric motor function in functional dyspepsia (FD). We evaluated total gastric emptying, initial proximal gastric distribution of meal (IPGD), proximal gastric emptying, basal tone, compliance and postprandial accommodation in the patients with FD relating to HP status.
METHODS
Of 25 subjects, 18 were HP positive and 7 were HP negative by the result of 13C urea breath test. A solid-phase scintigraphic gastric emptying and gastric barostat were performed.
RESULTS
In both HP-positive and HP-negative patients, sex, age, symptom score and body mass index were not different. Total gastric half-emptying time (101+/-13.9 min vs. 107+/-25.9 min), retention rate at 30 min (80.4+/-1.2% vs. 81.6+/-3.2%) and at 120 min (47.3+/-4.1% vs. 49.9+/-7.7%) were similar between the two groups. IPGD (69.4+/-4.1% vs. 64.6+/-11.1%) and proximal half-emptying time (37.9+/-5.2 min vs. 48.4+/-13.2 min) were not different between the two groups. Moreover, basal tone (60.8+/-3.4 ml vs. 65.0+/-7.0 ml), compliance (49.2+/-2.4 ml/mmHg vs. 37.6+/-5.7 ml/mmHg), and accommodation (207+/-46% vs. 137+/-75%) were not different between the two groups.
CONCLUSIONS
There was no association between HP infection and proximal gastric motor function in FD.

Keyword

Functional dyspepsia; Helicobacter pylori; Proximal motor function; Accommodation

MeSH Terms

Body Mass Index
Breath Tests
Compliance
Dyspepsia*
Gastric Emptying
Helicobacter pylori*
Helicobacter*
Humans
Meals
Urea
Urea
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