Korean J Pediatr.  2004 Jul;47(7):803-806.

Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome

• Chun KU
• Yun S
• Cha BH
• Lee HY

Abstract

Bronchiolitis Obliterans(BO) is one of the rare inflammatory lung disease that primarily affects bronchi and bronchioles, followed by partial or complete obstruction. In children, the etiology of BO has been under consideration, but infections and toxic inhalation, connective tissue diseases, lung transplantation, congestive pulmonary edema, etc., may be causes of BO. Even though steroid therapy was reported as an effective treatment, there are few data regarding the epidemiology, pathophysiology, long term prognosis and therapy. Here we describe a 5-year-old boy who presented with intractable wheezing associated with Stevens-Johnson syndrome after Varicella-Zoster virus infection and was diagnosed as BO through chest high-resolution computed tomography.

Keyword

Bronchiolitis obliterans; Stevens-Johnson syndrome; Herpesvirus 3; Human

MeSH Terms

Bronchi
Bronchioles
Bronchiolitis Obliterans*
Bronchiolitis*
Child
Child, Preschool
Connective Tissue Diseases
Epidemiology
Estrogens, Conjugated (USP)
Herpesvirus 3, Human
Humans
Inhalation
Lung Diseases
Lung Transplantation
Male
Prognosis
Pulmonary Edema
Respiratory Sounds
Stevens-Johnson Syndrome*
Thorax
Estrogens, Conjugated (USP)