- Drug Labeling Status of Culprit Drugs Inducing Severe Cutaneous Adverse Reactions
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Yeom HJ, Kim HHw, Kim HJ, Park S, Jang JY, Park GY, Kang DY, Kang HR
- KMID: 2534651
- .
- 2021 Sep;13(2):70-77.
- doi: 10.56142/2021.13.2.70
Objective: The labeling status of culprit drugs of Severe Cutaneous Adverse Reactions (SCAR) was evaluated by comparing the labeling status of the US Food and Drug Administration (FDA) to the... -
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- Clinical Features and Prognostic Factors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Retrospective Study of Data from 88 Patients
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Hong JY, Chung EH, Yang NG, Kim JY, Heo NH, Lee SH, Kim JE, Lee SY
- KMID: 2520798
- Korean J Dermatol.
- 2021 Sep;59(8):604-610.
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal acute hypersensitivity reactions that involve the skin and mucous membranes. Because they are relatively rare diseases, it is... -
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- Adult-onset Atypical Stevens-Johnson Syndrome with HLA-A*11:01 and HLA-A*31:01 Alleles
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Kim M, Chun YS, Kim KW
- KMID: 2516813
- J Korean Ophthalmol Soc.
- 2021 Jun;62(6):842-847.
- doi: 10.3341/jkos.2021.62.6.842
Purpose: We report a case of adult-onset atypical Stevens-Johnson syndrome (SJS) in which only the oral and ocular mucosae were involved, without skin lesions. Case summary: A 33-year-old man was... -
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- Acute and Chronic Ophthalmic Involvement, Severity, and Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
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Ganekal S, Nagarajappa A
- KMID: 2516663
- Korean J Ophthalmol.
- 2021 Jun;35(3):179-187.
- doi: 10.3341/kjo.2020.0118
Purpose: To study the ocular manifestations, its severity and sequelae in patients with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Methods: Prospective study of 44 consecutive patients (30 SJS and... -
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- Lamellar Graft of an Acellular, Preserved Human Cornea for Recurrent Anterior Granuloma in Stevens-Johnson Syndrome
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Lee SH, Bae SH, Kim KW
- KMID: 2511273
- J Korean Ophthalmol Soc.
- 2020 Nov;61(11):1358-1363.
- doi: 10.3341/jkos.2020.61.11.1358
Purpose: We describe a patient with Stevens-Johnson syndrome who exhibited recurrent anterior corneal granulomas after corneal perforation (despite multiple amniotic membrane [AM] transplantations); the patient was successfully treated by lamellar... -
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- Full-mouth rehabilitation in a Stevens-Johnson syndrome patient with severely worn dentition and abnormal root development
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Park YH, Ryu R, Ahn SG, Kim KA, Seo JM
- KMID: 2506887
- Oral Biol Res.
- 2020 Sep;44(3):118-126.
- doi: 10.21851/obr.44.03.202009.118
Stevens-Johnson syndrome (SJS) is a cytotoxic immune disorder that causes serious damage to the skin and mucous membranes. SJS is a rare disorder that is triggered by particular medications or... -
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- A Case of Generalized Seizure after Toxic Epidermal Necrolysis
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Kim MS, Kim YI, Choi H, Na CH, Shin BS
- KMID: 2504866
- Ann Dermatol.
- 2020 Aug;32(4):334-336.
- doi: 10.5021/ad.2020.32.4.334
Toxic epidermal necrolysis (TEN) is a severe mucocutaneousadverse reaction characterized by extensive necrosis and epidermaldetachment involving more than 30% of the bodysurface area (BSA). It is commonly triggered by antiepileptics,sulfonamide... -
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- Therapeutic Effects of Mesenchymal Stem Cells on a Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Model
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Park SY, Oh IY, Kim JH, Kim HJ, Seo B, Kwon OY, Song WJ, Kwon HS, Cho YS, Moon HB, Kim TB
- KMID: 2500193
- J Korean Med Sci.
- 2020 Apr;35(15):e130.
- doi: 10.3346/jkms.2020.35.e130
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are the most severe cutaneous drug hypersensitivity reactions, which are unpredictable adverse drug reactions. SJS/TEN is associated with significant mortality and morbidity; however,... -
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- Ribociclib-Related Stevens–Johnson Syndrome: Oncologic Awareness, Case Report, and Literature Review
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López-Gómez V, Yarza R, Muñoz-González H, Revilla E, Enrech S, González-Valle O, Tolosa P, Ciruelos E
- KMID: 2470903
- J Breast Cancer.
- 2019 Dec;22(4):661-666.
- doi: 10.4048/jbc.2019.22.e44
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering,... -
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- Anesthetic Management for an Eye Surgery in a Patient with Stevens-Johnson Syndrome
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Shin WJ, Park HJ, Lee CW, Park SH, Shon Y, Yeom JH
- KMID: 2470415
- Soonchunhyang Med Sci.
- 2019 Dec;25(2):132-134.
- doi: 10.0000/sms.2019.25.2.132
The Stevens-Johnson syndrome is a severe manifestation of erythema multiforme associated with multisystem involvement. It is extremely unusual for patients with this syndrome to present with indications for eye surgery.... -
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- Severe Cutaneous Adverse Reactions: A Single-Center Retrospective Study of 173 Patients in China
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Xu Z, Shen J, Yang Y, Yuan R, Xiang LF, Zhang C
- KMID: 2456232
- Ann Dermatol.
- 2019 Oct;31(5):545-554.
- doi: 10.5021/ad.2019.31.5.545
BACKGROUND: Severe cutaneous adverse reactions (SCAR) to drugs are a crucial public health issue and the use of systemic corticosteroids in SCAR has been controversial. OBJECTIVE: To analyze clinical features, causative... -
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- A Case of Secondary Milia Associated with Stevens-Johnson Syndrome
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Jung Y, Woo YR, Kim M, Park HJ
- KMID: 2465968
- Korean J Dermatol.
- 2019 Sep;57(8):510-511.
No abstract available. -
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- Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea
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Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH, Korean Registry of Severe Cutaneous Adverse Reactions Consortium
- KMID: 2452760
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):709-722.
- doi: 10.4168/aair.2019.11.5.709
PURPOSE: Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) to antiepileptic drug (AED), are rare, but... -
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- A Case of Stevens-Johnson Syndrome with Vanishing Bile Duct Syndrome
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An JH, Lee SG, Kim DH, Yoon MS, Lee HJ
- KMID: 2451587
- Korean J Dermatol.
- 2019 Jun;57(5):258-261.
Stevens-Johnson syndrome (SJS) is a serious and potentially life-threatening disease. Vanishing bile duct syndrome (VBDS) is a rare cause of progressive cholestasis. Both syndromes are usually associated with the use... -
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- Phenotypes of Severe Cutaneous Adverse Reactions Caused by Nonsteroidal Anti-inflammatory Drugs
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Lee SY, Nam YH, Koh YI, Kim SH, Kim S, Kang HR, Kim MH, Lee JG, Park JW, Park HK, La HO, Kim MY, Park SJ, Kwon YE, Jung JW, Kim SH, Kim CW, Yang MS, Kang MG, Lee JY, Kim JH, Kim SH, Hur GY, Jee YK, Jin HJ, Park CS, Jeong YY, Ye YM
- KMID: 2431853
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):212-221.
- doi: 10.4168/aair.2019.11.2.212
PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are common cause of severe cutaneous adverse reactions (SCARs). The present study aimed to investigate the characteristics of SCARs induced by NSAIDs in the Korean... -
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- Ocular Surface Reconstruction Using Circumferentially-trephined Autologous Oral Mucosal Graft Transplantation in Limbal Stem Cell Deficiency
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Choe HR, Yoon CH, Kim MK
- KMID: 2434301
- Korean J Ophthalmol.
- 2019 Feb;33(1):16-25.
- doi: 10.3341/kjo.2018.0111
PURPOSE: To investigate the effects of transplantation of a circumferentially-trephined autologous oral mucosal graft using a vacuum trephine on ocular surface reconstruction in patients with limbal stem cell deficiency. METHODS: Patients... -
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- Analysis of Individual Case Safety Reports of Severe Cutaneous Adverse Reactions in Korea
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Kang MG, Sohn KH, Kang DY, Park HK, Yang MS, Lee JY, Kang HR
- KMID: 2431638
- Yonsei Med J.
- 2019 Feb;60(2):208-215.
- doi: 10.3349/ymj.2019.60.2.208
PURPOSE: Despite morbidities and fatalities, nationwide epidemiologic data for severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms... -
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- Direct costs of severe cutaneous adverse reactions in a tertiary hospital in Korea
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Yang MS, Kim JY, Kang MG, Lee SY, Jung JW, Cho SH, Min KU, Kang HR
- KMID: 2452503
- Korean J Intern Med.
- 2019 Jan;34(1):195-201.
- doi: 10.3904/kjim.2015.365
BACKGROUND/AIMS: There are only a few reports on the direct costs of severe cutaneous adverse reactions (SCARs), including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and... -
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- The Therapeutic Effect of Sclerocorneal Lens in Coexisting Corneal Ectasia and Stevens-Johnson Syndrome
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Baek JU, Park CH, Na KS, Kim HS
- KMID: 2422586
- J Korean Ophthalmol Soc.
- 2018 Oct;59(10):968-973.
- doi: 10.3341/jkos.2018.59.10.968
PURPOSE: We report short-term treatment effects of a mini-scleral lens in patients with Stevens-Johnson syndrome and corneal ectasia. CASE SUMMARY: A 54-year-old female who had been diagnosed with Stevens-Johnson syndrome and... -
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- Genetic markers of severe cutaneous adverse reactions
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Jung JW, Kim JY, Park IW, Choi BW, Kang HR
- KMID: 2419997
- Korean J Intern Med.
- 2018 Sep;33(5):867-875.
- doi: 10.3904/kjim.2018.126
Adverse drug reactions can cause considerable discomfort. They can be life-threatening in severe cases, requiring or prolonging hospitalization, impeding proper treatment, and increasing treatment costs considerably. Although the incidence of... -
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