Korean J Anesthesiol.  2006 Nov;51(5):578-583. 10.4097/kjae.2006.51.5.578.

Changes in Jugular Venous Oxygen Saturation during Liver Transplantation

• Lee EH
• Shin K
• Kim JU
• Park JY
• Piao LZ
• Hwang GS

• KMID: 2034395
• DOI: http://doi.org/10.4097/kjae.2006.51.5.578

Abstract

BACKGROUND: Marked changes in systemic hemodynamics during liver transplantation may lead to changes in cerebral hemodynamics and metabolism. Therefore, continuous monitoring of the jugular venous oxygen saturation (SjvO2) may help the anesthetic management of liver transplantation.
METHODS
We observed changes in SjvO2 using a double lumen oximetry catheter for continuous monitoring and analyzed the correlation between SjvO2 and hemodynamic measurements in thirty patients undergoing liver transplantation.
RESULTS
There were no significant changes in SjvO2 compared to initial SjvO2 during liver transplantation. SjvO2, however, increased from 72.5 to 79.6 % (P < 0.05), before and after reperfusion. There was a weak correlation between changes in SjvO2 and cardiac output (r = 0.38, P < 0.05), whereas no correlation was found among changes in SjvO2 and arterial carbon dioxide tension, mean arterial pressure, central venous pressure, or mixed venous oxygen saturation before and after reperfusion.
CONCLUSIONS
SjvO2 that reflects changes in cerebral oxygen demand-supply balance was well maintained during liver transplantation except the reperfusion period. Continuous monitoring of changes in SjvO2 at this period may provide further insight to understand physiology of cerebral oxygenation during liver transplantation and merits further studies.

Keyword

end-stage liver disease; jugular venous oxygen saturation; liver transplantation

MeSH Terms

Arterial Pressure
Carbon Dioxide
Cardiac Output
Catheters
Central Venous Pressure
Hemodynamics
Humans
Liver Transplantation*
Liver*
Metabolism
Oximetry
Oxygen*
Physiology
Reperfusion
Carbon Dioxide
Oxygen