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Preoperative high-sensitivity troponin I and B-type natriuretic peptide, alone and in combination, for risk stratification of mortality after liver transplantation

Moon YJ, Kwon HM, Jung KW, Kim KS, Shin WJ, Jun IG, Song JG, Hwang GS

Background: Given the severe shortage of donor liver grafts, coupled with growing proportion of cardiovascular death after liver transplantation (LT), precise cardiovascular risk assessment is pivotal for selecting recipients who...
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Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo

Chun KH, Jin HC, Kang KS, Chang TS, Hwang GS

Activation of osteoclast and inactivation of osteoblast result in loss of bone mass with bone resorption, leading to the pathological progression of osteoporosis. The receptor activator of NF-κB ligand (RANKL)...
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Systolic anterior motion of mitral chordae tendineae: prevalence and clinical implications in liver transplantation

Kwon HM, Kim KS, Hwang GS

Background: Although systolic anterior motion (SAM) of the mitral valve anterior leaflet is well-known to cause hemodynamic perturbation in many anesthetic situations, the prevalence and clinical implication of SAM of...
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The Mental Health and Occupational Characteristic of Horse Stable Hand Workers in Korea

Kim KW, Lee SG, Hwang GS

The horse stable hand workers are one of the most important occupations in horse-racing industry. However, suicide problem of the horse stable hand workers in Korea has raised the necessity...
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Lipid-Core Plaque Assessed by Near-Infrared Spectroscopy and Procedure Related Microvascular Injury

Yang HM, Yoon MH, Lim HS, Seo KW, Choi BJ, Choi SY, Hwang GS, Tahk SJ

BACKGROUND AND OBJECTIVES: Microvascular damage due to distal embolization during percutaneous coronary intervention (PCI) is an important cause of periprocedural myocardial infarction. We assessed the lipid-core plaque using near-infrared spectroscopy...
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Preoperative echocardiographic evaluation of cardiac systolic and diastolic function in liver transplant recipients with diabetes mellitus: a propensity-score matched analysis

Kwon HM, Jeong Y, Kim KS, Jung KW, Moon YJ, Hwang GS

BACKGROUND: Diabetes mellitus (DM) increases risk of heart failure. It has been shown that diabetes leads to DM-cardiomyopathy, characterized by systolic and diastolic dysfunction. Pre-transplant diastolic dysfunction, has been associated...
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Designing Tyrosinase siRNAs by Multiple Prediction Algorithms and Evaluation of Their Anti-Melanogenic Effects

Kwon OS, Kwon SJ, Kim JS, Lee G, Maeng HJ, Lee J, Hwang GS, Cha HJ, Chun KH

Melanin is a pigment produced from tyrosine in melanocytes. Although melanin has a protective role against UVB radiation-induced damage, it is also associated with the development of melanoma and darker...
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Cardiovascular dysfunction and liver transplantation

Kwon HM, Hwang GS

Cardiovascular complications have emerged as the leading cause of death after liver transplantation, particularly among those with advanced liver cirrhosis. Therefore, a thorough and accurate cardiovascular evaluation with clear comprehension...
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Quality of Anticoagulation and Treatment Satisfaction in Patients with Non-Valvular Atrial Fibrillation Treated with Vitamin K Antagonist: Result from the KORean Atrial Fibrillation Investigation II

Oh S, Kim JS, Oh YS, Shin DG, Pak HN, Hwang GS, Choi KJ, Kim JB, Lee MY, Park HW, Kim DK, Jin ES, Park J, Oh IY, Shin DH, Park HS, Kim JH, Kim NH, Ahn MS, Seo BJ, Kim YJ, Kang S, Lee J, Kim YH

BACKGROUND: Vitamin K antagonist (VKA) to prevent thromboembolism in non-valvular atrial fibrillation (NVAF) patients has limitations such as drug interaction. This study investigated the clinical characteristics of Korean patients treated...
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Pretransplant diastolic wall strain assessed by transthoracic echocardiography and its implication on posttransplant survival rate in liver transplantation

Sang BH, Kim JW, Yoo JI, Bang YS, Choi YS, Moon YJ, Hwang GS, Lim YS

BACKGROUND: In cirrhotic patients, left ventricular diastolic dysfunction is associated with poor outcomes. Diastolic wall strain (DWS) is a new index of left ventricular diastolic function that correlates with the...
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Design of Korean Noninvasive Risk Evaluation Study for Sudden Cardiac Death from Infarction or Heart Failure: Myocardial infarction study of K-REDEFINE registry

Park SJ, Hwang GS, Nam GB, Park HW, Chung JW, Shin SY, Kim SM, Kim JH, Lee YS, Park YM, Kim JY, Kim DH, Kim DK, Namgung J, Shin DH, Choi JH, Park HS, Choi JI, Kim JS, Cha TJ, Park SW, Uhm JS, Kim NH, Ahn M, Shin DG, Jang N, Park M, Kim JS, K-REDEFINE investigators

BACKGROUND AND OBJECTIVES: Despite significant advances in the treatment of acute myocardial infarction (MI), the prevention of sudden cardiac death (SCD), the most common mode of death in patients with...
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Anatomical Discrepancy Between The Coronary Sinus and the Mitral Annulus by Fluoroscopy

Kim JW, Hwang GS, Seo KW, Park JS, Yang HM, Lim HS, Choi BJ, Choi SY, Yoon MH, Tahk SJ

BACKGROUND AND OBJECTIVES: Intracardiac electrocardiograms (ECGs) from the coronary sinus (CS) provide important information for identifying a left-sided bypass tract. However, a previous study revealed an anatomical discrepancy between the...
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Cerebral air embolism and subsequent transient neurologic abnormalities in a liver transplant recipient following the removal of the pulmonary artery catheter from the central venous access device: a case report

Kim SK, Jun IG, Jang DM, Lim J, Hwang GS, Kim YK

Cerebral air embolism is a rare but potentially life-threatening complication. We experienced a living-donor liver transplant recipient who presented with unexpected cerebral air embolism and transient neurologic abnormalities that subsequently...
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Arrhythmogenic potential develops rapidly at graft reperfusion before the start of hypotension during living-donor liver transplantation

Lee HM, Park SK, Moon YJ, Kim JW, Kim SK, Sang BH, Seo DK, Yoo BW, Hwang GS

BACKGROUND: Detailed profiles of acute hypothermia and electrocardiographic (ECG) manifestations of arrhythmogenicity were examined to analyze acute hypothermia and ventricular arrhythmogenic potential immediately after portal vein unclamping (PVU) in living-donor...
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Design of Korean Noninvasive Risk Evaluation Study for Sudden Cardiac Death from Infarction or Heart Failure: Heart failure study of K-REDEFINE registry

Park SJ, Hwang GS, Nam GB, Park HW, Chung JW, Shin SY, Kim SM, Kim JH, Lee YS, Park YM, Kim JY, Kim DH, Kim DK, Namgung J, Shin DH, Choi JH, Park HS, Choi JI, Kim JS, Cha TJ, Park SW, Uhm JS, Kim NH, Ahn M, Shin DG, Jang N, Park M, Kim JS, K-REDEFINE investigators

BACKGROUND AND OBJECTIVES: Sudden cardiac death (SCD) is one of the most common causes of death in patients with heart failure (HF). However, there are no available data on SCD...
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Time Variance of Electrocardiographic Transmural Dispersion in Acute Myocardial Infarction

Park JS, Hwang GS, Kim SM, Seo KW, Choi BJ, Choi SY, Yoon MH, Shin JH, Tahk SJ

BACKGROUND AND OBJECTIVES: The mechanism responsible for lethal ventricular arrhythmia (LVA) after acute myocardial infarction (AMI) remains unclear. SUBJECTS AND METHODS: The corrected QT interval (QTc) and interval from the peak...
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Transthoracic echocardiography probe in an anesthesiologist's hand: utility in the operating room

Hwang GS

With increased availability and feasibility of bedside sonography, point-of-care ultrasonography is a rapidly developing field in many fields of emergency and intensive care medicine. Although anesthesiologists frequently encounter severe hypotension...
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A comparison of systolic and diastolic time variation with pulse pressure variation as a predictor of fluid responsiveness during pediatric liver transplantation

Moon YJ, Lee HM, Kim JW, Chung HJ, Lee S, Huh IY, Hwang GS

BACKGROUND: In pediatric patients, dynamic preload indices to predict fluid responsiveness remain controversial. Because each beat of blood pressure (BP) - waveform - contains evidence of a systolic and diastolic...
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Usefulness of Hyperemic Microvascular Resistance Index as a Predictor of Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction

Jin X, Yoon MH, Seo KW, Tahk SJ, Lim HS, Yang HM, Choi BJ, Choi SY, Hwang GS, Shin JH, Park JS

BACKGROUND AND OBJECTIVES: Microvascular function is a useful predictor of left ventricular functional changes in patients with ST-segment elevation myocardial infarction (STEMI). We evaluated the usefulness of the hyperemic microvascular...
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Vagolytic atropine attenuates cerebral vasodilation response during acute orthostatic hypotension

Choi WJ, Lee K, Kim YK, Song KJ, Jeong SM, Hwang GS

BACKGROUND: Atropine is an anticholinergic drug which is commonly used in clinical practice. The effect of parasympathetic block with atropine on dynamic cerebrovascular regulation remains unclear. This study was aimed...
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