Korean Circ J.  1994 Aug;24(4):624-632. 10.4070/kcj.1994.24.4.624.

The Effect of Non-Ionic Contrast Media on Q-T Interval and ST-T Wave of ECG during Coronary Angiography

• Kim SY
• Jeon YD
• Yoon YB
• Kim YJ
• Lee HS
• Yoo SW
• Moon ES
• Sung SK
• Lee HC

• KMID: 2029388
• DOI: http://doi.org/10.4070/kcj.1994.24.4.624

Abstract

BACKGROUND
During coronary angiography, some electrocardiographic changes occured due to contrast media, which do life threatening influences.
METHODS
We compared the electrocardiographic changes which were induced by injection of three radiopaque contrast media during selective coronary angiography in 49 patients with chest pain. One of the contrast media was high osmolar ionic(Urografin_76) and the another was low osmolar ionic(Hexabrix) and the last was non-ionic(Ioversol). Electrocardiograms were obtained before, during and after selective coronary angiography.
RESULTS
The changes of S-T segment or T were decreased in non-ionic group rather than high osmolar or ionic group. And there was significant Q-Tc interval prolongation among all three groups except comparision of low osmolar ionic contrast dye and non-ionic contrast dye in left coronary angiography.
CONCLUSION
Non-ionic low osmolar contrast media was safer than high osmolar or ionic contrast medial because of lesser change of Q-Tc interval during selective coronary angiography.

Keyword

Ionic and non-ionic; Osmolarity; Urografin 76; Hexabrix; Ioversol

MeSH Terms

Chest Pain
Contrast Media*
Coronary Angiography*
Diatrizoate Meglumine
Electrocardiography*
Humans
Ioxaglic Acid
Osmolar Concentration
Contrast Media
Diatrizoate Meglumine
Ioxaglic Acid