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Prescreening skin test effectiveness in predicting hypersensitivity to iodinated contrast media

Kim TB

Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue owing to widespread use of computed tomography (CT) examinations. The question of whether routine performance of skin tests...
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Change of culprit agent prevents recurrent hypersensitivity reactions to iodinated contrast media

Cha MJ, Lee W

With technical advances in computed tomography and the introduction of non-ionic low- or iso-osmolar iodinated contrast media (ICM), the use of ICM and the occurrence of ICM-related hypersensitivity reactions (HSRs)...
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Prevention of infection from contrast agents

Jung SE

Until now, automatic contrast agent injector syringes licensed for consecutive one-time use have been employed with a number of patients. In 2016, regulation of automatic injector syringes ensured their single...
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Near-Infrared Contrast Agents for Bone-Targeted Imaging

Jung JS, Jo D, Jo G, Hyun H

BACKGROUND: For the bone-specific imaging, a structure-inherent targeting of bone tissue recently has been reported a new strategy based on incorporation of targeting moieties into the chemical structure of near-infrared...
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Emerging Role of Hepatobiliary Magnetic Resonance Contrast Media and Contrast-Enhanced Ultrasound for Noninvasive Diagnosis of Hepatocellular Carcinoma: Emphasis on Recent Updates in Major Guidelines

Kim TH, Yoon JH, Lee JM

Hepatocellular carcinoma (HCC) can be noninvasively diagnosed on the basis of its characteristic imaging findings of arterial phase enhancement and portal/delayed “washout” on computed tomography (CT) and magnetic resonance imaging...
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Clinical Manifestations of Contrast Media Extravasation in the Emergency Department and the Ward

Bae JG, Kang TK, Ryu S, Cho SJ, Oh SC, Kim HJ, Choi SW, Lee SH, Kang MJ

PURPOSE: Contrast media extravasation (CME) is an adverse reaction after administration of contrast media during CT examinations. The purpose of this study was to evaluate the frequency, management, and outcomes...
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Diagnostic Significance of pH-Responsive Gd³⁺-Based T₁ MR Contrast Agents

Bhuniya S, Hong KS

We discuss recent advances in Gd-based T₁-weighted MR contrast agents for the mapping of cellular pH. The pH plays a critical role in various biological processes. During the past two...
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Management of Adverse Reactions to Iodinated Contrast Media for Computed Tomography in Korean Referral Hospitals: A Survey Investigation

Han S, Yoon SH, Lee W, Choi YH, Kang DY, Kang HR

OBJECTIVE: To evaluate the current status of managing adverse reactions to iodinated contrast media (ICM) for computed tomography in referral hospitals in South Korea compared with hospitals in other countries. MATERIALS...
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Low-Tube-Voltage CT Urography Using Low-Concentration-Iodine Contrast Media and Iterative Reconstruction: A Multi-Institutional Randomized Controlled Trial for Comparison with Conventional CT Urography

Kim SY, Cho JY, Lee J, Hwang SI, Moon MH, Lee EJ, Hong SS, Kim CK, Kim KA, Park SB, Sung DJ, Kim Y, Kim YM, Jung SI, Rha SE, Kim DW, Lee H, Shim Y, Hwang I, Woo S, Choi HJ

OBJECTIVE: To compare the image quality of low-tube-voltage and low-iodine-concentration-contrast-medium (LVLC) computed tomography urography (CTU) with iterative reconstruction (IR) with that of conventional CTU. MATERIALS AND METHODS: This prospective, multi-institutional, randomized...
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Clinical characteristics of adverse reaction to radiocontrast media in children - A single center experience

Kim MJ, Lee BR, Choi YH, Kang DY, Kang HR, Suh DI

PURPOSE: Radiocontrast media are widely used in medical imaging to improve diagnostic accuracy. However, studies on the adverse reactions of radiocontrast media in children are limited. We aimed to describe...
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Radiocontrast media-induced acute generalized exanthematous pustulosis: A safe administration of alternative radiocontrast media using patch tests

Kim SH, Lee SY, Choi YH, Kim CH, Hyun IK, Choi JH

Acute generalized exanthematous pustulosis (AGEP) is rarely caused by radiocontrast media (RCM). The role of skin tests for the diagnosis and evaluation of cross-reactivity in a delayed type of RCM-induced...
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Naphthalocyanines as contrast agents for photoacoustic and multimodal imaging

Chitgupi U, Lovell JF

Naphthalocyanines (Ncs) are a family of aromatic small molecule with large near infrared extinction coefficients, making them appealing contrast agent candidates for photoacoustic imaging (PAI). Depending on the substitutions on...
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Incidence of Breakthrough Reaction in Patients with Prior Acute Allergic-Like Reactions to Iodinated Contrast Media according to the Administration Route

Kim YS, Choi YH, Cho YJ, Lee S, Yoon SH, Park CM, Kang HR

OBJECTIVE: This study assessed the risk of acute allergic-like reactions (AARs) after extravascular administration of iodinated contrast media (ICM) in at-risk patients compared with that after intravascular ICM administration. MATERIALS AND...
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Electronic Consultation Support System for Radiocontrast Media Hypersensitivity Changes Clinicians' Behavior

Yang MS, Choi SI, Song WJ, Kim SH, Cho SH, Min KU, Kim JH, Chang YS

PURPOSE: Patients with a history of radiocontrast media (RCM) hypersensitivity can be overlooked, resulting in repeated reactions. Therefore, a consultation support system for RCM hypersensitivity has been in operation at...
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Magnetic Resonance Imaging for Colorectal Cancer Metastasis to the Liver: Comparative Effectiveness Research for the Choice of Contrast Agents

Seo N, Park MS, Han K, Lee KH, Park SH, Choi GH, Choi JY, Chung YE, Kim MJ

PURPOSE: This study was conducted to compare the diagnostic performance and early recurrence rate between gadoxetic acid–enhanced magnetic resonance imaging (Gd-EOB-MRI) and magnetic resonance imaging (MRI) with extracellular contrast agent...
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Transient Orbitofacial Angioedema due to Intravenous Iodinated Contrast Media During Computed Tomography: CT Findings

Min S, Kim ES, Lee Y, Lee K

Orbitofacial angioedema is one of the common contrast-induced adverse reactions. The symptoms are recognized, based on the patient's clinical complaints. Based on prior research findings, there were no reports about...
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Synthesis of ultrasound contrast agents: characteristics and size distribution analysis (secondary publication)

Lee HJ, Yoon TJ, Yoon YI

PURPOSE: The purpose of this study was to establish a method for ultrasound (US) contrast agent synthesis and to evaluate the characteristics of the synthesized US contrast agent. METHODS: A US...
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Influence of ultrasound contrast agents on spectral Doppler analysis in recipients of liver transplantation

Cho YS, Kim KW, Jang HY, Kim BH, Lee J, Song GW, Lee SG, Munkhbaatar D

BACKGROUND/AIMS: Clinical validation is required to determine whether Doppler measurements are comparable before and after administering ultrasound contrast agent (USCA). The purpose of this study is to explore whether the...
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A Case Report on a Severe Anaphylaxis Reaction to Gadolinium-Based MR Contrast Media

Park J, Kim TH, Park CM, Yoon SH, Lee W, Kang HR, Choi YH

Acute hypersensitivity reactions to gadolinium-based magnetic resonance (MR) contrast media have been shown to have a much lower incidence and they are generally milder in terms of severity than acute...
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Prevalence and clinical features of hypersensitivity reaction to contrast media after prescreening skin test

Park BB, Park CH, Nho IY, Kim HS, Kang NK, Chang SI, Kim JM

PURPOSE: Hypersensitivity reactions to contrast media (CM) are one of the most common causes of drug adverse reactions. The overall prevalence of immediate hypersensitivity reaction (IHR) was 0.16%–7.7% to nonionic...
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