J Korean Epilepsy Soc.
2012 Jun;16(1):30-32.
Successful Treatment of Intractable Hiccup with Levetiracetam
- Affiliations
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- 1Department of Neurology, Hallym University College of Medicine, Seoul, Korea. hksong@hallym.or.kr
Abstract
- Hiccups may be considered a form of myoclonus of diaphragm. Valproic acid has been considered the drug of choice in treatment of intractable hiccups; however, its various adverse events limit its use in the clinical basis, especially in elderly or complicated patients. Levetiracetam was known as a safe antiepileptic drug. However, the anti-hiccup property of the levetiracetam has been rarely reported. We report a 69-year old male patient who developed sudden persistent hiccups and was successfully treated with levetiracetam. Levetiracetam should be considered as alternative treatment option in selected patients with intractable hiccups.