J Korean Epilepsy Soc.  2012 Jun;16(1):30-32.

Successful Treatment of Intractable Hiccup with Levetiracetam

Affiliations
  • 1Department of Neurology, Hallym University College of Medicine, Seoul, Korea. hksong@hallym.or.kr

Abstract

Hiccups may be considered a form of myoclonus of diaphragm. Valproic acid has been considered the drug of choice in treatment of intractable hiccups; however, its various adverse events limit its use in the clinical basis, especially in elderly or complicated patients. Levetiracetam was known as a safe antiepileptic drug. However, the anti-hiccup property of the levetiracetam has been rarely reported. We report a 69-year old male patient who developed sudden persistent hiccups and was successfully treated with levetiracetam. Levetiracetam should be considered as alternative treatment option in selected patients with intractable hiccups.

Keyword

Intractable hiccups; Levetiracetam; Valproic acid

MeSH Terms

Aged
Diaphragm
Hiccup
Humans
Male
Myoclonus
Piracetam
Valproic Acid
Piracetam
Valproic Acid
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