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Comparison of the effect of removing artificial dental plaque depending on various interdental cleaning products on the interdental surface of zirconia crowns

Kim HW, Song HK, Park EJ

Purpose The purpose of this study is to compare five interdental cleansing products' effectiveness on removing artificial dental plaque on the interdental space of zirconia crowns. Materials and Methods A model with abutments...
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The Role of Sex-specific Long Non-coding RNAs in Cancer Prevention and Therapy

Song HK, Kim SY

The functions of a large number of non-coding genes in human DNA have yet to be accurately identified. Long non-coding RNA (lncRNA) measuring 10 kb or less in length regulates...
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Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources

Park JW, Lee SJ, Kim JE, Kang MJ, Bae SJ, Choi YJ, Gong JE, Kim KS, Jung YS, Cho JY, Choi YS, Hwang DY, Song HK

Sepsis, one of the most fatal diseases in the world, is known to culminate in multiple organ failure due to an uncontrolled inflammatory response. Hence, the use of animal models...
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Korean Neurological Terminology

Ha SW, Kim SB, Kim BK, Cho SG, Song Hk

Experts have communicated and developed field of study through scientific terminology. However, medical terminologies are no longer used only by experts. As technology advances and society becomes more complex, the...
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Sex-Biased Molecular Signature for Overall Survival of Liver Cancer Patients

Kim SY, Song HK, Lee SK, Kim SG, Woo HG, Yang J, Noh HJ, Kim YS, Moon A

Sex/gender disparity has been shown in the incidence and prognosis of many types of diseases, probably due to differences in genes, physiological conditions such as hormones, and lifestyle between the...
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Bone Substitutes: From Basic to Current Update

Han JS, Song HK

Bone substitutes are being used increasingly in bony surgery as more than two million bone grafts are performed worldwide per year. Autobone grafts represent the gold standard for bone grafting,...
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Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

Hwang DJ, Kwon KC, Song HK, Kim KS, Jung YS, Hwang DY, Cho JY

MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is commonly used to induce nigrostriatal defects to induce parkinsonism and/or parkinsonian syndrome, to replicate the lesions seen in Parkinson's disease (PD), with use in numerous PD models...
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Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks

Kang MJ, Kim JE, Park JW, Choi HJ, Bae SJ, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

In our efforts to understand the systemic features of tumors, the importance of animal models is increasing due to the recent growth in the development of immunotherapy and targeted therapies....
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The Usefulness of Perforator Flaps for the Definitive Management of Exposed Hardware in Patients with Lower Extremity Fracture

Kim SM, Jeong KS, Song HK, Park MC, Park DH, Lee IJ

PURPOSE: Hardware exposure after the lower extremity fractures operation is challenging to manage and requires long-term treatment. The traditional management of exposed hardware usually includes hardware removal. The purpose of...
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Renal Cholesterol Embolism during Warfarin Treatment

Yoon S, Bae JS, Lee JH, Song HK, Yoo J, Kang DG, Seo JY, Nam ES, Shin DH, Kim Y

Cholesterol embolization syndrome (CES) usually occurs after endovascular procedures, it may also occurs after using anticoagulants and thrombolytics. We report a case of 66-year-old man with sudden elevation of creatinine...
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Long-term study of the association of adipokines and glucose variability with diabetic complications

Cha JJ, Min HS, Kim K, Lee MJ, Lee MH, Kim JE, Song HK, Cha DR, Kang YS

BACKGROUND/AIMS: Recent studies have suggested an important role of adipokines in the development of insulin resistance and diabetes mellitus. The clinical relevance of adipokines on long-term outcomes in patients with...
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Comparison of scopolamine-induced cognitive impairment responses in three different ICR stocks

Yoon WB, Choi HJ, Kim JE, Park JW, Kang MJ, Bae SJ, Lee YJ, Choi YS, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

Cognitive impairment responses are important research topics in the study of degenerative brain diseases as well as in understanding of human mental activities. To compare response to scopolamine (SPL)-induced cognitive...
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Comparison of the anesthetic effects of 2,2,2-tribromoethanol on ICR mice derived from three different sources

Lee MR, Suh HR, Kim MW, Cho JY, Song HK, Jung YS, Hwang DY, Kim KS

This study was conducted to compare the anesthetic effects of 2,2,2-tribromoethanol (TBE, Avertin®) in ICR mice obtained from three different sources. TBE (2.5%) was intraperitoneally injected at three doses: high-dose...
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Acute Ischemic Stroke in Moyamoya Syndrome Associated with Thyrotoxicosis

Kang D, Seong GH, Bae JS, Lee JH, Song HK, Kim Y

BACKGROUND: A few cases of moyamoya syndrome associated with thyrotoxicosis have been reported. However, studies on the association of hyperthyroidism with moyamoya syndrome are insufficient. CASE REPORT: Here we report a...
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Crotonis Fructus Extract Inhibits 12-O-Tetradecanoylphorbol-13-Acetate-Induced Expression of Matrix Metalloproteinase-9 via the Activator Protein-1 Pathway in MCF-7 Cells

Song HK, Lee GS, Park SH, Noh EM, Kim JM, Ryu DG, Jung SH, Youn HJ, Lee YR, Kwon KB

PURPOSE: Metastatic cancers spread from the primary site of origin to other parts of the body. Matrix metalloproteinase-9 (MMP-9) is essential in metastatic cancers owing to its major role in...
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Impact of inflammatory bowel disease on daily life: an online survey by the Korean Association for the Study of Intestinal Diseases

Kim YS, Jung SA, Lee KM, Park SJ, Kim TO, Choi CH, Kim HG, Moon W, Moon CM, Song HK, Na SY, Yang SK, Korean Association for the Study of Intestinal Diseases (KASID)

BACKGROUND/AIMS: Inflammatory bowel disease (IBD) is a chronic disabling gastrointestinal disorder that diminishes the quality of life of the affected individuals. Limited data are available regarding the impact of IBD...
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Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources

Yun WB, Kim HR, Kim JE, Choi JY, Lee MR, Park JJ, Song BR, Jung YS, Song HK, Cho JY, Kim KS, Hwang DY

C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and...
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Comparative analysis of basal locomotor activity-related metabolic phenotypes between C57BL/6 mice and ICR mice substrains derived from three different sources

Hwang DJ, Song HK, Kim KS, Jung YS, Hwang DY, Cho JY

Animal model, as an indispensable tool for scientific purposes of biomedical researches and clinical application, is a commonly used in various researches. Regarding to this, it is necessary to establish...
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Comparison of humoral and cell-mediated immunity in three different C57BL/6N mouse substrains

Kim HR, Choi JY, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

Adaptive immunity is a type of immune response mediated by T and B cells, and is important response for immune response amplification and memory. In this study, the adaptive immunologic...
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Comparative study of the immunological characteristics of three different C57BL/6N mouse substrains

Choi JY, Kim HR, Kim KS, Jung YS, Cho JY, Hwang DY, Song HK

Inbred mice, a systematically developed homogeneous animal, have been developed to maintain experimental reproducibility and to minimize experimental variables in animal-based studies. In particular, C57BL/6 mice are frequently used in...
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