J Korean Soc Magn Reson Med.  2011 Aug;15(2):160-164. 10.13104/jksmrm.2011.15.2.160.

Image Findings of Primary Squamous Cell Carcinoma of the Pancreas in Patient with Chronic Pancreatitis: A Case Report

• Kim JB
• Kim MY
• Suh CH
• Lee KY
• Joo YC
• Cho JY

• KMID: 2000065
• DOI: http://doi.org/10.13104/jksmrm.2011.15.2.160

Abstract

Squamous cell carcinoma of the pancreas is a rare, uncommon tumor that is characterized by squamous metaplasia of the ductal columnar cells. We report the image findings of a rare case of the pancreatic squamous cell carcinoma associated with chronic pancreatitis.

Keyword

Pancreas, squamous cell carcinoma; Magnetic resonance (MR); Computed tomography (CT); Endoscopic ultrasonography (EUS)

MeSH Terms

Carcinoma, Squamous Cell
Humans
Metaplasia
Pancreas
Pancreatitis, Chronic

Figure

• 

  Fig. 1 (a) Contrast enhanced CT scan shows heterogeneously peripheral enhancing solid mass (arrowheads) and perilesional invasion (white arrows) on equilibrium phase. Note dense calcifications (black arrow) within diffuse atrophic change of pancreas, suggesting chronic pancreatitis. (b) EUS (endoscopic ultrasonography) shows lobulating solid mass (arrowheads) in tail portion of pancreas, and multiple hyperechogeic stones (arrows) in tail of pancreas. (c) Axial T1-weighted MR image shows iso-signal intensity of the pancreatic mass lesion (arrow heads) than that of spleen. (d) Axial T2-weighted MR image shows heterogeneously hyper intense mass (arrow heads) in pancreatic tail and perilesional infiltration in splenic hilum (white arrows). Signal intensity of mass lesion is higher than that of spleen. Intraductal stone (black arrow) and parenchyma atrophy of pancreas are suggestive findings of chronic pancreatitis. (e) Surgical specimen shows solid mass (arrowheads) in distal pancreas extends to the peripancreatic soft tissue and hilum of spleen (S). Note the small intraductal and stones (arrow). (f) Histologic section demonstrating a squamous cell carcinoma with intraparenchymal tumor nest (arrow heads), keratin pearl (white arrow), and clear cell change (black arrow) (H & E stain, 200 × magnification).

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