Korean J Dermatol.  2003 Dec;41(12):1703-1705.

A Case of Kikuchi's Disease (Histiocytic Necrotizing Lymphadenopathy) Showing Typical Histopathologic Findings in Cutaneous Lesion

• Kim SH
• Sim HJ
• Doh KS
• Jang MS
• Suh KS
• Kim ST

Abstract

Kikuchi's disease(Histiocytic necrotizing lymphadenitis) is an idiopathic, self-limiting disease typically affecting cervical lymph nodes in young adults. Cutaneous involvement has been reported in 16-40%. We report a case of Kikuchi's disease in 10-year-old female that showed asymptomatic erythematous papules on the face accompanied by cervical lymphadenopathy. The histopathologic examination of the skin revealed diffuse dermal lymphohistiocytic infiltrate, a large amount of nuclear dust with absence of neutrophils, which is characteristic of Kikuchi's disease. In general, histopathologic findings of skin biopsy show a mirror image of that of lymph nodes involved in Kikuchi's disease. Therefore, it is important to recognize cutaneous manifestations of this entity, because we can avoid invasive lymph node biopsy. if skin lesions involved show typical histopathologic findings of Kikuchi's disease.

Keyword

Kikuchi's disease; Cutaneous manifestations; Histopathologic findings

MeSH Terms

Biopsy
Child
Dust
Female
Histiocytic Necrotizing Lymphadenitis*
Humans
Lymph Nodes
Lymphatic Diseases
Neutrophils
Skin
Young Adult
Dust