Korean J Dermatol.  2021 Jan;59(1):54-57.

Kikuchi’s Disease Manifested as Non-Specific Facial Skin Lesions: A Case Report

• Lim JS
• Kwon ES
• Myung KB
• Cheong SH

Abstract

Kikuchi’s disease, also referred to as histiocytic necrotizing lymphadenopathy, is a benign self-limiting lymphadenitis accompanied by mild fever and night sweats. This disorder usually affects young women and presents with non-specific cutaneous findings. A 15-year-old female adolescent presented with erythematous papules and plaques on both cheeks accompanied by fever, night sweats, and right cervical lymphadenopathy. Histopathological evaluation of a skin biopsy specimen showed mild perivascular and periadnexal infiltration in the dermis. Fine-needle aspiration biopsy of lymph nodes revealed coagulative necrosis with lymphocytic, histiocytic, and karyorrhectic debris. We present a rare case of Kikuchi’s disease that was diagnosed based on histopathological evaluation of skin and lymph node specimens.

Keyword

Kikuchi’s disease; Histiocytic necrotizing lymphadenitis; Karyorrhectic