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Tuberc Respir Dis.  2006 Sep;61(3):285-288. 10.4046/trd.2006.61.3.285.

Exacerbation of Sarcoidosis Following Interferon-alpha Therapy for Chronic Active Hepatitis C

Affiliations
  • 1Department of Internal Medicine, Ewha Women University College of Medicine, Seoul, Korea. jinhwalee@ewha.ac.kr
  • 2Department of Radiology, Ewha Women University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Ewha Women University College of Medicine, Seoul, Korea.

Abstract

Interferon alpha is an immunomodulator that is used as an antiviral agent to treat chronic active viral hepatitis C. However, interferon can induce or exacerbate sarcoidosis. We report a case of 42-year-old man with an exacerbation of pulmonary sarcoidosis after the cessation of interferon and ribavirin therapy for chronic hepatitis C. The patient's sarcoidosis improved spontaneously and he continues to be monitored regularly without steroid therapy.

Keyword

Hepatitis C; Interferon; Sarcoidosis

MeSH Terms

Adult
Hepatitis C
Hepatitis C, Chronic
Hepatitis, Chronic*
Humans
Interferon-alpha*
Interferons
Ribavirin
Sarcoidosis*
Sarcoidosis, Pulmonary
Interferon-alpha
Interferons
Ribavirin
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