- Different Quantitative Interferon-γ Response in Active Tuberculosis of Various Primary Infection Sites
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Lee H, Kim KH
- KMID: 2466767
- Lab Med Online.
- 2020 Jan;10(1):58-65.
- doi: 10.3343/lmo.2020.10.1.58
BACKGROUND: The quantitative interferon (IFN)-γ response in the IFN-γ release assay (IGRA) has been investigated to predict progression from Mycobacterium tuberculosis infection to active tuberculosis (TB). However, the significance of... -
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- Circulating MicroRNAs and T-Cell Cytokine Expression Are Associated With the Characteristics of Asthma Exacerbation
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Wardzyńska A, Pawełczyk M, Rywaniak J, Kurowski M, Makowska J, Kowalski M
- KMID: 2462577
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):125-136.
- doi: 10.4168/aair.2020.12.1.125
PURPOSE: Immunological mechanisms underlying asthma exacerbation have not been elucidated. The aim of this study was to assess the associations of various asthma exacerbation traits with selected serum microRNA (miRNA)... -
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- Recurrent Optic Neuritis and Acute Encephalopathy with Myelin Oligodendrocyte Glycoprotein Antibodies in a Korean Child
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Hwang JE, Kim SH, Park S
- KMID: 2470412
- Soonchunhyang Med Sci.
- 2019 Dec;25(2):121-124.
- doi: 10.0000/sms.2019.25.2.121
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases are reported to have distinct pathogenic mechanisms, clinical courses, and therapeutic implications in comparison to other acquired demyelinating syndromes. Here, we report the case... -
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- Prevalence and Risk Factors of Latent Tuberculosis Infection among Healthcare Workers
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Lee S, Lee YL, Kim YC, Kim EJ, Heo JY, Choi YH
- KMID: 2467904
- Korean J healthc assoc Infect Control Prev.
- 2019 Dec;24(2):52-59.
- doi: 10.14192/kjicp.2019.24.2.52
BACKGROUND: Due to occupational exposure, healthcare workers (HCW) face an increased risk of tuberculosis (TB) infection. This study was conducted to assess the prevalence and risk factors of latent tuberculosis... -
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- New Potential Therapies for Chronic Hepatitis B
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Yoo SH, Kwon JH
- KMID: 2464185
- Korean J Gastroenterol.
- 2019 Nov;74(5):267-273.
- doi: 10.4166/kjg.2019.74.5.267
A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective... -
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- Viperin Differentially Induces Interferon-Stimulated Genes in Distinct Cell Types
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Kim JJ, Kim KS, Eom J, Lee JB, Seo JY
- KMID: 2461197
- Immune Netw.
- 2019 Oct;19(5):e33.
- doi: 10.4110/in.2019.19.e33
Viperin is an IFN-stimulated gene (ISG)-encoded protein that was identified in human primary macrophages treated with IFN-γ and in human primary fibroblasts infected with cytomegalovirus (CMV). This protein plays multiple... -
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- The Interplay between Host Immunity and Respiratory Viral Infection in Asthma Exacerbation
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Hossain FM, Choi JY, Uyangaa E, Park SO, Eo SK
- KMID: 2461195
- Immune Netw.
- 2019 Oct;19(5):e31.
- doi: 10.4110/in.2019.19.e31
Asthma is one of the most common and chronic diseases characterized by multidimensional immune responses along with poor prognosis and severity. The heterogeneous nature of asthma may be attributed to... -
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- Good Agreement between an Interferon Gamma Release Assay and Tuberculin Skin Tests in Testing for Latent Tuberculosis Infection among HIV-Infected Patients in Indonesia
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Reviono R, Saptawati , Redhono D, Suryawati
- KMID: 2460035
- J Korean Med Sci.
- 2019 Oct;34(40):e259.
- doi: 10.3346/jkms.2019.34.e259
BACKGROUND: Latent tuberculosis infection is a condition where there is a persistent immune response to Mycobacterium tuberculosis without clinical manifestations of tuberculosis. Currently, there is no gold standard to diagnose... -
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- Platelet count is associated with sustained virological response rates in treatments for chronic hepatitis C
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Jun BG, Park EJ, Lee WC, Jang JY, Jeong SW, Kim YD, Cheon GJ, Cho YS, Lee SH, Kim HS, Lee YN, Kim SG, Kim YS, Kim BS
- KMID: 2457022
- Korean J Intern Med.
- 2019 Sep;34(5):989-997.
- doi: 10.3904/kjim.2017.322
BACKGROUND/AIMS: This study was conducted to clarify the sustained virological response (SVR) prediction ability of baseline and treatment-related factors in patients with chronic hepatitis C virus (HCV) infection. METHODS: This retrospective... -
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- Magnolol exerts anti-asthmatic effects by regulating Janus kinase-signal transduction and activation of transcription and Notch signaling pathways and modulating Th1/Th2/Th17 cytokines in ovalbumin-sensitized asthmatic mice
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Huang Q, Han L, Lv R, Ling L
- KMID: 2450492
- Korean J Physiol Pharmacol.
- 2019 Jul;23(4):251-261.
- doi: 10.4196/kjpp.2019.23.4.251
Allergic asthma, is a common chronic inflammatory disease of the airway presenting with airway hyperresponsiveness and airway remodelling. T helper cells-derived cytokines are critically associated with asthma pathogenesis. Janus kinase-signal... -
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- Comparison of the virulence of Streptococcus pneumoniae in ICR mouse stocks of three different origins
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Kim JY, Seo SM, Lee HK, Kim HW, Choi YK
- KMID: 2456057
- Lab Anim Res.
- 2019 Jun;35(1):23-29.
- doi: 10.1186/s42826-019-0002-4
Streptococcus pneumoniae causes many people to suffer from pneumonia, septicemia, and other diseases worldwide. To identify the difference in susceptibility of and treatment efficacy against S. pneumoniae in three ICR... -
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- Upregulation of PITX2 Promotes Letrozole Resistance Via Transcriptional Activation of IFITM1 Signaling in Breast Cancer Cells
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Xu YY, Yu HR, Sun JY, Zhao Z, Li S, Zhang XF, Liao ZX, Cui MK, Li J, Li C, Zhang Q
- KMID: 2464405
- Cancer Res Treat.
- 2019 Apr;51(2):576-592.
- doi: 10.4143/crt.2018.100
PURPOSE: Although the interferon α (IFNα) signaling and the paired-like homeodomain transcription factor 2 (PITX2) have both been implicated in the progression of breast cancer (BCa), it remains obscure whether... -
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- Aquatic Exercise at Thermoneutral Water Temperature Enhances Antitumor Immune Responses
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Lee B, Kim G, Jo Y, Lee B, Shin YI, Hong C
- KMID: 2444158
- Immune Netw.
- 2019 Apr;19(2):e10.
- doi: 10.4110/in.2019.19.e10
Despite the broad rehabilitative potential of aquatic exercises, the relationship between aquatic exercise and the immune system has not been fully elucidated to date. In particular, there are few specific... -
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- The Performance of the Agility System for Interferon Gamma Release Assay Using QuantiFERON TB Gold In-Tube Assay
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Seok K, Shin S
- KMID: 2446696
- J Lab Med Qual Assur.
- 2019 Mar;41(1):29-38.
- doi: 10.15263/jlmqa.2019.41.1.29
BACKGROUND: As stated in ‘The Action Strategy for Tuberculosis-Free Korea,’ last March, high-throughput, large-scale analytical instruments for interferon gamma release assays (IGRA) are demanded by many clinical laboratories using the... -
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- Aggressive Contact Investigation of In-Hospital Exposure to Active Pulmonary Tuberculosis
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Park SY, Lee EJ, Kim YK, Lee SY, Kim GE, Jeong YS, Kim JH, Kim TH
- KMID: 2438309
- J Korean Med Sci.
- 2019 Feb;34(7):e58.
- doi: 10.3346/jkms.2019.34.e58
BACKGROUND: In-hospital detection of newly diagnosed active pulmonary tuberculosis (TB) is important for prevention of potential outbreaks. Here, we report our experience of the aggressive contact investigation strategy in a... -
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- N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
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Kim HR, Kim KW, Kim BM, Lee KA, Lee SH
- KMID: 2452505
- Korean J Intern Med.
- 2019 Jan;34(1):210-219.
- doi: 10.3904/kjim.2016.329
BACKGROUND/AIMS: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA). METHODS: After RA synovial fibroblasts were stimulated... -
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- Real-World Effectiveness of Disease-Modifying Therapies in Korean Patients with Relapsing Multiple Sclerosis
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Kim SH, Park MS, Kim W, Huh SY, Shin HJ, Hyun JW, Kim HJ
- KMID: 2451141
- J Clin Neurol.
- 2019 Jan;15(1):20-26.
- doi: 10.3988/jcn.2019.15.1.20
BACKGROUND AND PURPOSE: This study assessed the long-term outcomes of disease-modifying therapies (DMTs) in Korean multiple sclerosis (MS) patients treated in real-world clinical settings in Korea. METHODS: We retrospectively evaluated the... -
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- Expression of Immunoproteasome Subunit LMP7 in Breast Cancer and Its Association with Immune-Related Markers
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Lee M, Song IH, Heo SH, Kim YA, Park IA, Bang WS, Park HS, Gong G, Lee HJ
- KMID: 2437601
- Cancer Res Treat.
- 2019 Jan;51(1):80-89.
- doi: 10.4143/crt.2017.500
PURPOSE: In the presence of interferon, proteasome subunits are replaced by their inducible counterparts to form an immunoproteasome (IP) plays a key role in generation of antigenic peptides presented by... -
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- Gene Expression Profiles of Th1-type Chemokines in Whole Blood of Mycobacterium avium subsp. paratuberculosis-Infected Cattle
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Shin MK, Park HE, Park HT, Jung M, Kang HL, Baik SC, Lee WK, Jung YH, Yoo HS
- KMID: 2452065
- J Bacteriol Virol.
- 2018 Dec;48(4):130-136.
- doi: 10.4167/jbv.2018.48.4.130
Johne's disease (JD) is a chronic, debilitating disease of ruminants including cows, and is caused by Mycobacterium avium subsp. paratuberculosis (MAP). MAP is not only important in animal husbandry, but... -
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- Mucosal Immunity Related to FOXP3⺠Regulatory T Cells, Th17 Cells and Cytokines in Pediatric Inflammatory Bowel Disease
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Cho J, Kim S, Yang DH, Lee J, Park KW, Go J, Hyun CL, Jee Y, Kang KS
- KMID: 2429597
- J Korean Med Sci.
- 2018 Dec;33(52):e336.
- doi: 10.3346/jkms.2018.33.e336
BACKGROUND: We aimed to investigate mucosal immunity related to forkhead box P3 (FOXP3+) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). METHODS:... -
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