- Ombitasvir/paritaprevir/ritonavir+dasabuvir and ribavirin associated drug-induced liver injury and syndrome of inappropriate secretion of anti-diuretic hormone: A case report
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Kumar R, Hsiang JC, Tan J, Thurairajah PH
- KMID: 2459794
- Clin Mol Hepatol.
- 2019 Sep;25(3):326-330.
- doi: 10.3350/cmh.2018.0063
No abstract available. -
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- Platelet count is associated with sustained virological response rates in treatments for chronic hepatitis C
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Jun BG, Park EJ, Lee WC, Jang JY, Jeong SW, Kim YD, Cheon GJ, Cho YS, Lee SH, Kim HS, Lee YN, Kim SG, Kim YS, Kim BS
- KMID: 2457022
- Korean J Intern Med.
- 2019 Sep;34(5):989-997.
- doi: 10.3904/kjim.2017.322
BACKGROUND/AIMS: This study was conducted to clarify the sustained virological response (SVR) prediction ability of baseline and treatment-related factors in patients with chronic hepatitis C virus (HCV) infection. METHODS: This retrospective... -
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- Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome
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Yoo JR, Kim SH, Kim YR, Lee KH, Oh WS, Heo ST
- KMID: 2457321
- Korean J Intern Med.
- 2019 Jul;34(4):902-909.
- doi: 10.3904/kjim.2016.194
BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not... -
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- Efficacy of L-carnitine on ribavirin-induced hemolytic anemia in patients with hepatitis C virus infection
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Sato S, Moriya K, Furukawa M, Saikawa S, Namisaki T, Kitade M, Kawaratani H, Kaji K, Takaya H, Shimozato , Sawada Y, Seki K, Kitagawa K, Akahane T, Mitoro A, Okura Y, Yamao J, Yoshiji H
- KMID: 2447252
- Clin Mol Hepatol.
- 2019 Mar;25(1):65-73.
- doi: 10.3350/cmh.2018.0070
BACKGROUND/AIMS: L-carnitine not only alleviates hyperammonemia and reduces muscle cramps in patients with liver cirrhosis, but also improves anemia in patients with chronic hepatitis and renal dysfunction. This study prospectively... -
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- Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease
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Choi JH, Jeong K, Kim SM, Ko MK, You SH, Lyoo YS, Kim B, Ku JM, Park JH
- KMID: 2427027
- J Vet Sci.
- 2018 Nov;19(6):788-797.
- doi: 10.4142/jvs.2018.19.6.788
In many countries, vaccines are used for the prevention of foot-and-mouth disease (FMD). However, because there is no protection against FMD immediately after vaccination, research and development on antiviral agents... -
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- Efficacy and safety of sofosbuvir plus ribavirin for Korean patients with hepatitis C virus genotype 2 infection: A retrospective multi-institutional study
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Kim YM, Kim SB, Song IH, Lee SH, Kim HS, Lee TH, Kang YW, Kim SH, Lee BS, Chae HB, Song MJ, Jang JW, Ko SY, Lee JD
- KMID: 2428759
- Clin Mol Hepatol.
- 2018 Sep;24(3):311-318.
- doi: 10.3350/cmh.2017.0070
BACKGROUND/AIMS: Sofosbuvir plus ribavirin is a standard treatment for patients infected with chronic hepatitis C virus (HCV) genotype 2 in Korea. The purpose of this study was to examine the... -
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- Does the old-fashioned sofosbuvir plus ribavirin treatment in genotype 2 chronic hepatitis C patients still works for Koreans?
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Yeon JE
- KMID: 2428755
- Clin Mol Hepatol.
- 2018 Sep;24(3):294-296.
- doi: 10.3350/cmh.2018.1009
No abstract available. -
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- Strategies Against Severe Fever with Thrombocytopenia Syndrome Increasing in Korea
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Yoo JR, Heo ST
- KMID: 2435670
- Korean J Blood Transfus.
- 2018 Aug;29(2):117-129.
- doi: 10.17945/kjbt.2018.29.2.117
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease that is caused by the genus phlebovirus in the family Bunyaviridae. The syndrome is characterized by fever, gastrointestinal... -
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- Hepatitis C virus infection in chronic kidney disease: paradigm shift in management
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Kim SM, Song IH
- KMID: 2415992
- Korean J Intern Med.
- 2018 Jul;33(4):670-678.
- doi: 10.3904/kjim.2018.202
Hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is associated with increased liver-related morbidity and mortality rates, accelerated progression to end-stage renal disease, and risk of cardiovascular events.... -
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- Treatment with Sofosbuvir and Daclatasvir (with or without Ribavirin) Improves Patient Reported Outcomes in Hepatitis C
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de Medeiros LPJ, Lima MB, Pires MM, Maciel AM, Medeiros R, Donadel MD, Pereira IM, Leão FM, Pires LE, Rzetelna H, Brandão-Mello CE
- KMID: 2413256
- Osong Public Health Res Perspect.
- 2018 Apr;9(2):50-58.
- doi: 10.24171/j.phrp.2018.9.2.03
OBJECTIVES: To evaluate the impact of 3 treatment regimens upon health-related quality of life and work productivity using patient-reported outcomes (PROs) in chronic hepatitis C infected patients: sofosbuvir (SOF) +... -
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- In Vitro Antiviral Activity of Sakuranetin against Human Rhinovirus 3
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Choi HJ
- KMID: 2402588
- Osong Public Health Res Perspect.
- 2017 Dec;8(6):415-420.
- doi: 10.24171/j.phrp.2017.8.6.09
OBJECTIVES: Rhinoviruses (RVs) cause common cold and are associated with exacerbation of chronic inflammatory respiratory diseases. Until now, no clinically effective antiviral chemotherapeutic agents to treat diseases caused by human... -
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- Clinical implication of serum uric acid level in pegylated interferon and ribavirin combination therapy for chronic hepatitis C infection
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Oh IS, Won JW, Kim HJ, Lee HW
- KMID: 2396760
- Korean J Intern Med.
- 2017 Nov;32(6):1010-1017.
- doi: 10.3904/kjim.2016.405
BACKGROUND/AIMS: Combined treatment of pegylated interferon-α (PEG-IFN) and ribavirin (RBV) has long been accepted as the standard treatment for chronic hepatitis C virus (HCV) infection. Many predictive factors for treatment... -
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- Healthcare Costs for Chronic Hepatitis C in South Korea from 2009 to 2013: An Analysis of the National Health Insurance Claims' Data
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Ki M, Choi HY, Kim KA, Jang ES, Jeong SH
- KMID: 2395389
- Gut Liver.
- 2017 Nov;11(6):835-842.
- doi: 10.5009/gnl17034
BACKGROUND/AIMS: The introduction of direct-acting antivirals (DAA) in 2013 revolutionized hepatitis C virus (HCV) treatment, offering a cure rate >90%. However, this therapy is expensive, and estimations of the number... -
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- Meta-analysis of the Efficacy and Safety of Grazoprevir and Elbasvir for the Treatment of Hepatitis C Virus Infection
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Kang MG, Kang MJ, Ji E, Yoo BK
- KMID: 2405669
- Korean J Clin Pharm.
- 2017 Sep;27(3):150-160.
- doi: 10.24304/kjcp.2017.27.3.150
OBJECTIVE: Recently, a fixed combination of grazoprevir and elbasvir (GE) has been introduced to the arsenal of chemotherapeutics to fight against this virus. The study aimed to provide information on... -
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- Direct Acting Antiviral Agents in Korean Patients with Chronic Hepatitis C and Hemophilia Who Are Treatment-Naïve or Treatment-Experienced
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Lee HW, Yoo KY, Won JW, Kim HJ
- KMID: 2389361
- Gut Liver.
- 2017 Sep;11(5):721-727.
- doi: 10.5009/gnl17209
BACKGROUND/AIMS: Chronic hepatitis C (CHC) is a major comorbidity in patients with hemophilia. METHODS: Patients (n=30) were enrolled between September 2015 and April 2016. Twenty-six patients were genotype 1 (1b, n=21;... -
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- Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus
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Tamai H, Ida Y, Kawashima , Shingaki N, Shimizu R, Moribata K, Nasu T, Maekita T, Iguchi M, Kato J, Nakao T, Kitano M
- KMID: 2412236
- Gut Liver.
- 2017 Jul;11(4):551-558.
- doi: 10.5009/gnl16525
BACKGROUND/AIMS: The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such... -
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- In vitro antiviral activity of ribavirin against severe fever with thrombocytopenia syndrome virus
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Lee MJ, Kim KH, Yi J, Choi SJ, Choe PG, Park WB, Kim NJ, Oh MD
- KMID: 2387719
- Korean J Intern Med.
- 2017 Jul;32(4):731-737.
- doi: 10.3904/kjim.2016.109
BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV), a novel bunyavirus. As yet, there is no effective... -
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- Prevalence and Incidence of Depression during Interferon-Based Antiviral Therapy in Chronic Hepatitis C Patients in the Republic of Korea
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Baeg JY, Kim IH, Seo SY, Kim YS, Jung EU, Cho J, Chung JW, Jang ES, Kim JW, Jeong SH
- KMID: 2412217
- Gut Liver.
- 2017 May;11(3):426-433.
- doi: 10.5009/gnl16242
BACKGROUND/AIMS: The association between depression and chronic hepatitis C virus (HCV) infection or pegylated interferon α and ribavirin therapy (PR therapy) has not been extensively studied in Korea. We aimed... -
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- Association of Changes in Mood Status and Psychosocial Well-Being with Depression During Interferon-Based Treatment for Hepatitis C
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Choi JS, Kim W, Sohn BK, Lee JY, Jung HY, Oh S, Joo SK, Kim HY, Jung YJ
- KMID: 2378647
- Psychiatry Investig.
- 2017 May;14(3):314-324.
- doi: 10.4306/pi.2017.14.3.314
OBJECTIVE: The aims of this prospective study were to investigate temporal changes in mood status and distress level, as well as the development of depression, during pegylated interferon (PEG-IFN)-based treatment... -
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- Clinical Characteristics and Treatment Outcome of Peginterferon Plus Ribavirin in Patients Infected with Genotype 6 Hepatitis C Virus in Korea: A Multicenter Study
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Shin SR, Kim YS, Lim YS, Lee JS, Lee JW, Kim SM, Jeong SH, Sohn JH, Lee MS, Park SH
- KMID: 2412194
- Gut Liver.
- 2017 Mar;11(2):270-275.
- doi: 10.5009/gnl16163
BACKGROUND/AIMS: Because of the limited geographic distribution, there have been insufficient data regarding hepatitis C virus (HCV) genotype 6 in Korea. This study aimed to investigate the clinical characteristics and... -
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