Korean J Dermatol.  2008 Jun;46(6):809-811.

A Case of Vitiligo in a Hepatitis C Patient after Pegylated Interferon Treatment

Affiliations
  • 1Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. hykang@ajou.ac.kr

Abstract

The use of pegylated interferon (PEG-IFN) and ribavirin is considered standard therapy for patients with chronic hepatitis C. The treatment has been linked with a number of dermatologic manifestations such as alopecia, skin rash, pruritus, injection site inflammation and occasionally, with vitiligo. We report a case of vitiligo that occurred during treatment with PEG-IFN and ribavirin in a hepatitis C patient. The autoimmune adverse effects of IFN therapy should be considered in the treatment of vitiligo in such patients.

Keyword

Hepatitis C; Pegylated Interferon; Ribavirin; Vitiligo

MeSH Terms

Alopecia
Exanthema
Hepatitis
Hepatitis C
Hepatitis C, Chronic
Humans
Inflammation
Interferons
Pruritus
Ribavirin
Vitiligo
Interferons
Ribavirin
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