Ewha Med J.  1979 Dec;2(4):191-194. 10.12771/emj.1979.2.4.191.

Effect of Different Vitamin E-deficient Basal Diets on Hepatic Catalase and Microsomal Cytochrome P-450 and b5 in Rats

Affiliations
  • 1Department of Biochemistry, Ewha Womans University School of Medicine, Korea.

Abstract

Male Wistar rats maintained for a period of 6 weeks on a basal vitamin E-deficiency diet consisting of 70% sucrose, 20% vatamin-free casein, 4% tocopherol, stripped lard, 4% salt mixture, and 2% tocopherol-free vitamin fortification mixture were used to compare two sets of commonly used salt mixture(salt mixture USP XIV versus Briggs' salt mixture). Among the rats maintained on the deficient diets for 6 weeks, only that received the combination of Briggs' salt mixture showed a significantly lower level of hepatic catalase activity, cytochrome P-450, and b5 compared to the corresponding control animals. Since the most striking differences in these diets are in their contest of iron, it appears that these two dietary constituents may intact in modulating the effect of vitamin E on hepatic hemoproteins.


MeSH Terms

Animals
Caseins
Catalase*
Cytochrome P-450 Enzyme System*
Cytochromes*
Diet*
Humans
Iron
Male
Rats*
Rats, Wistar
Strikes, Employee
Sucrose
Tocopherols
Vitamin E
Vitamins*
Caseins
Catalase
Cytochrome P-450 Enzyme System
Cytochromes
Iron
Sucrose
Tocopherols
Vitamin E
Vitamins
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