J Korean Neurosurg Soc.  1988 Aug;17(4):625-630.

The Comparision of Histologic & Electrophysiologic Changing Area after Monopolar Coagulation in the Rabbit Brain

Affiliations
  • 1Department of Neurosurgery, Yeungnam University, College of Medicine, Taegu, Korea.

Abstract

Lesions with controlled monopolar coagulation were generated in the cerebral cortex of 20 healthy rabbits. With 28 watts monopolar coagulation, average diameter of histologically changed area around lesion was aout 7.5mm with using Evans blue dye technique. At same time, EEGs in three points, which were 5mm, 10mm & 15mm distant from the coagulated lesion site, were cheched before and just after coagulation. In results, the frequency of EEG was slightly decreased after coagulation, but there were no relation with distance from lesion. But the amplitudes of EEG were decreased as 51.2 micro v(61.2%), 42.9 micro v(3.9) and 34.0 micro v(25.3%) after coagulation, which depended on the distance from site of coagulation. That means electrophysiologically changed area after coaguation was far beyond the histologically changed area.

Keyword

Monopolar coagulation; Histological changes; Rabbit EEG; Electrophysiologic changes

MeSH Terms

Brain*
Cerebral Cortex
Electroencephalography
Evans Blue
Rabbits
Evans Blue
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