J Korean Surg Soc.  1997 May;52(5):755-759.

Apocrine Carcinoma of the Breast: The report of 2 cases

• Jung KH
• Lee ES
• Bae JW
• Koo BH

Abstract

Apocrine carcinoma is an uncommon, poorly characterized type of breast tumor. The histologic characteristics of apocrine epithelium in malignant breast lesion were first noted by Krompecher(1916), while the first detailed description of an apocrine carcinoma is credited to Ewing in 1928. The reported incidence of apocrine carcinoma is approximately 0.4% of breast cancers. Apocrine carcinoma has distinct histologic and ultrastructural features that distinguish it as a specialized form of infiltrating ductal carcinoma. The finding of a uniform pattern of apocrine differentiation with dense granularity typifying the majority of cells characterizes this variant. We experienced two cases of invasive apocrine carcinoma of the breast and report with a review of the related literature.

Keyword

Breast cancer; Invasive apocine carcinoma

MeSH Terms

Breast Neoplasms
Breast*
Carcinoma, Ductal
Epithelium
Incidence