Korean J Anesthesiol.
1987 Jun;20(3):319-325. 10.4097/kjae.1987.20.3.319.
Cardiovascular and Neuromuscular Effects of Vecuronium Bromide (Norcuron)
- Affiliations
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- 1Department of Anesthesiology, College of Medicine, Seoul National University, Korea.
- KMID: 1933284
- DOI: http://doi.org/10.4097/kjae.1987.20.3.319
Abstract
- We studied the cardiovascular and neuromuscular effects of Norcuron (a new nondepo larizing muscle relaxant) in ASA Claas I patients under halothane and nitrous oxide ane-sthegia. The onset time of Norcuron was 1.06+/-0.27 win, and Clinical duration of action time was 41.49+/-5.53 min and recovery index was 16.38+/-2.30 min and total duration of action time was 67.04 +/-14.42 min.. after volus injection Norcuron 0.1 mg/kg. Norcuron did not change mean arterial presaure, heart rate and histamine secretions and had not arrythmogemic effect on heart rhythm. We conclude that vecuronium bromide (Norcuron) produces a excellent neuromuscular blockade of short duration with little cardiovascular changes and histamine releaae.
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