Korean J Anesthesiol.  1992 Feb;25(1):153-157. 10.4097/kjae.1992.25.1.153.

Comparison of Maximum Inspiratory Pressure and Train of Four Ratio at Neuromuscular Recovery of Vecuronium after Neuroleptanesthesia

• Kim YJ

• KMID: 2237048
• DOI: http://doi.org/10.4097/kjae.1992.25.1.153

Abstract

In this study, we have assessed correlation between maximum inspiratory pressure(MIP) and train of four(TOF) ratio. During neuroleptanesthesia, vecuronium was administered intravenously to 45 patients under TOF monitoring. MIP and TOF ratio was measured every 5 minutes at recovery from neuromuscular blockade. The results were as follows: 1) During neuromuscular recovery, good correlation existed between MIP and TOF ratio. 2) When TOF ratio was 0.65+/-0.05, MIP was 30.4I+/-4.47cmH,O. 3) When TOF ratio was 0.85+/-0.05, MIP was 52.18+/-4.34 cmH,O. These results were suggested that TOF ratio of above 0.8 was consistent with ability to protect the patient's airway against aspiration and obstruction.

Keyword

Neuroleptanesthesia; Neuromuscular relaxant; vecuronium; Monitoring; maximum inspiratory pressure; Train of four ratio

MeSH Terms

Humans
Neuromuscular Blockade
Vecuronium Bromide*
Vecuronium Bromide