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Characteristics of Pruritus according to Morphological Phenotype of Psoriasis and Association with Neuropeptides and Interleukin-31

Park SM, Kim GW, Kim HS, Ko HC, Kim MB, Kim BS

BACKGROUND: Pruritus is a common symptom in psoriasis. However, few studies have assessed the characteristics of pruritus according to morphological phenotypes of psoriasis. OBJECTIVE: To investigate the characteristics of pruritus according...
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The effect of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion

Hwang S, Chung CJ, Choi YJ, Kim T, Kim KH

OBJECTIVE: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. METHODS: Sixty male Sprague–Dawley rats were...
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Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review

Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P

PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic...
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Anaphylaxis to Chlorpheniramine Maleate and Literature Review

Choi YW, Jung MJ, Kim HO, Chung BY, Park CW

Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We...
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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Evaluation of symptoms and symptom combinations in histamine intolerance

Schnedl WJ, Lackner S, Enko D, Schenk M, Holasek SJ, Mangge H

BACKGROUND/AIMS: Food intolerance/malabsorption, particularly histamine intolerance (HIT), may cause nonspecific functional gastrointestinal and extraintestinal symptoms. We evaluated gastrointestinal and extraintestinal symptoms in patients with HIT. METHODS: In an analysis of outpatients'...
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Emerging Therapies in Chronic Spontaneous Urticaria

Min TK, Saini SS

Chronic spontaneous urticaria (CSU) is characterized by typically short-lived and fleeting wheals, angioedema or both, which occur spontaneously and persist for longer than 6 weeks. This term is applied to...
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria

Ulambayar , Lee H, Yang EM, Park HS, Lee K, Ye YM

Translationally controlled tumor protein (TCTP) is also known as histamine releasing factor as it has the ability to activate mast cells. To investigate the role of TCTP in the pathogenesis...
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Omalizumab as a Succesfull Therapy in Normocomplementemic Urticarial Vasculitis: A Series of Four Patients and Review of the Literature

Degirmentepe EN, Kızıltac K, Etikan P, Singer R, Memet B, Kocaturk E

Urticarial vasculitis is an eruption characterized by inflamed itchy or painful red papules or plaques that resemble urticaria but last longer than 24 hours and heal with residual pigmentation or...
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Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Jiao J, Zhang L

The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can...
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A case of nizatidine-induced immediate hypersensitivity

Park SW, Heo YJ, Lee KS, Kwon JW

Nizatidine is a histamine Hâ‚‚ receptor antagonist that inhibits stomach acid production and is commonly used in the treatment of peptic ulcer and gastroesophageal reflux. Hâ‚‚ receptor antagonists are typically...
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Drug eruption by antihistamine mistaken for chronic urticaria in a child

Lee GM, Chu SY, Kang SY, Kim HB, Park JS, Kim JK

Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g.,...
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Characteristics of poisoning in younger children according to different forms of the drugs

Jang M, Ko Y, Yang HW, Lee J

PURPOSE: This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms. METHODS: This was a retrospective analysis based...
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Allergy to carminic acid: in vitro evidence of involvement of protein-binding hapten

Osumi M, Yamaguchi , Sugimoto N, Suzukawa M, Arai H, Akiyama H, Nagase H, Ohta K

We previously described a rare case of anaphylaxis presumably induced by carminic acid in cochineal dye used as a food additive. In this study, highly pure carminic acid was added...
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Urticaria Multiforme with Residual Pigmentation: Two Case Reports

Roh D, Kim WI, Yang MY, Lee WK, Kim TW, Park SM, Lee HJ, Kim GW, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2433642
  • Korean J Dermatol.
  • 2019 Jan;57(1):32-35.
Urticaria multiforme is a cutaneous condition observed in children. This self-limited condition is characterized by well-circumscribed, annular, and erythematous wheals, which spontaneously disappear within a few days. Patients commonly present...
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Updated treatment guideline of chronic spontaneous urticaria

Roh JY

Chronic spontaneous urticaria (CSU), also known as chronic idiopathic urticaria, is a common chronic inflammatory skin disorder that has a prevalence of 0.5% to 1% in the general population. It...
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Antipsychotics for patients with pain

Shin SW, Lee JS, Abdi S, Lee SJ, Kim KH

Going back to basics prior to mentioning the use of antipsychotics in patients with pain, the International Association for the Study of Pain (IASP) definition of pain can be summarized...
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Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults

Kim MY, Etherton-Beer C, Kim CB, Yoon JL, Ga H, Kim HC, Song JS, Kim KI, Won CW

BACKGROUND: Korea has recently attained the aged society status and the growth rate of the aging population will be among the most rapid worldwide. The objective of this study was...
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Phloxine O, a Cosmetic Colorant, Suppresses the Expression of Thymic Stromal Lymphopoietin and Acute Dermatitis Symptoms in Mice

Lee HE, Yang G, Kim KB, Lee BM, Lee JY

Cosmetics are primarily applied to the skin; therefore, the association of cosmetic dyes with skin diseases or inflammation is a topic of great interest. Thymic stromal lymphopoietin (TSLP) is an...
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