Korean J Med.  2004 Nov;67(Suppl 3):S881-S886.

A case of peritoneal metastasis from gastric cancer successfully treated with docetaxel and cisplatin chemotherapy

• Ahn JS
• Yang DH
• Byun JR
• Kim YK
• Cho SH

Abstract

In case of unresectable or metastatic gastric cancer, though many trials have been going, treatment results are poor yet. We report a patient with peritoneal metastasis from gastric cancer effectively treated with docetaxel and cisplatin chemotherapy. The patient was a 33 year-old man who was confirmed poorly differenciated adenocarcinoma of stomach 5 years ago. At the diagnosis, the stage of gastric cancer was T2N3M0. He underwent subtotal gastrectomy with Billoth II anastomosis and 6th cycles of postoperative adjuvant chemotherapy consisting of FAMTX. After that, there was no evidence of recurrence. Three years later, he was admitted to our hospital complaining of abdominal pain and distension. Abdominal CT revealed that recurred gastric cancer in anastomotic site with carcinomatous peritonei and multiple lymphadenopathy. He was performed chemotherapy combined with docetaxel (75 mg/m2) and cisplatin (75 mg/m2). After 3rd chemotherapy, follow up abdominal CT showed nearly complete regression of bowel loops, lymph node and ascites. After completion of 7th cycles of chemotherapy, it remained as complete response for recurred gastric cancer and he has no evidence of recurrence for over 2 years.

Keyword

Peritoneal neoplasm; Gastric cancer; Docetaxel; Cisplatin

MeSH Terms

Abdominal Pain
Adenocarcinoma
Adult
Ascites
Chemotherapy, Adjuvant
Cisplatin*
Diagnosis
Drug Therapy*
Follow-Up Studies
Gastrectomy
Humans
Lymph Nodes
Lymphatic Diseases
Neoplasm Metastasis*
Peritoneal Neoplasms
Recurrence
Stomach
Stomach Neoplasms*
Tomography, X-Ray Computed
Cisplatin