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Clinical Significance of Epstein-Barr Virus and Helicobacter pylori Infection in Gastric Carcinoma

Noh JH, Shin JY, Lee JH, Park YS, Lee IS, Kim GH, Na HK, Ahn JY, Jung KW, Kim DH, Choi KD, Song HJ, Lee GH, Jung HY

Background/Aims: Epstein-Barr virus (EBV) and Helicobacter pylori (HP) coinfection may synergistically induce severe inflammatory responses in the stomach tissue, increasing the risk of developing gastric cancer. We aimed to analyze...
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Gastric wall abscess after endoscopic submucosal dissection

Yu SJ, Lee SH, Yoon JS, Lee HS, Jee SR

Gastric wall abscess, a localized form of phlegmonous gastritis, is a rare complication of endoscopic resection. We report the first case of gastric wall abscess developing after endoscopic submucosal dissection...
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The Study on the Sleep Duration of Gastric Cancer Survivor in Korean Adults: The 7th (2016–2018) Korea National Health and Nutrition Examination Survey

Joo EH, Ryou IS, Lee SW, Lee HS, Shim KW, Sohn YJ

Background: The relationship between cancer survival and sleep duration remains inconsistent, especially for gastric cancer. This study investigated the relationship between sleep duration and gastric cancer survival among Korean adults. Methods:...
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Impact of Cardiovascular Diseases on Mortality in Gastric Cancer Patients with Preexisting Chronic Disease

Han KT, Kim DW, Kim W

Purpose: Chronic diseases and cardiovascular diseases (CVD) have been independently linked to poorer cancer outcomes. This study investigated whether gastric cancer patients with hypertension, diabetes, or dyslipidemia have higher mortality...
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Prognostic Perspectives of STING and PD-L1 Expression and Correlation with the Prognosis of Epstein-Barr Virus-Associated Gastric Cancers

Sun Q, Fu Y, Chen X, Li L, Wu H, Liu Y, Xu H, Zhou G, Fan X, Xia H

Background/Aims: Epstein-Barr virus-associated gastric cancers (EBVaGCs) have unique molecular and clinicopathological characteristics. The cyclic GMP-AMP synthase-stimulator of interferon genes (STING) pathway is recently recognized as the critical innate immunity against...
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Impact of the COVID-19 Pandemic on Gastric Cancer Screening in South Korea: Results From the Korean National Cancer Screening Survey (2017–2021)

Lee K, Suh M, Jun JK, Choi KS

Purpose: The coronavirus disease 2019 (COVID-19) pandemic has significantly disrupted cancer screening services worldwide. We aimed to measure the impact of COVID-19 on gastric cancer screening rates based on age,...
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Molecular Pathology of Gastric Cancer

Kim M, Seo AN

Gastric cancer (GC) is one of the most common lethal malignant neoplasms worldwide, with limited treatment options for both locally advanced and/or metastatic conditions, resulting in a dismal prognosis. Although...
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Apatinib as a Third-Line Treatment for HER2-Positive Metastatic Gastric Cancer: A Multi-Center Single-Arm Cohort Study

Zhang X, Huo H, Nie Y, Xue J, Yuan Z, Zhang Z

Purpose: Treatment options are limited after the failure of first-and second-line treatments in patients with HER2+ metastatic gastric cancer (mGC). The present study aimed to explore the efficacy, safety, and...
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PLK2 Single Nucleotide Variant in Gastric Cancer Patients Affects miR-23b-5p Binding

Dominkuš PP, Mesic A, Hudler P

Purpose: Chromosomal instability is a hallmark of gastric cancer (GC). It can be driven by single nucleotide variants (SNVs) in cell cycle genes. We investigated the associations between SNVs in...
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Safe Discharge Criteria After Curative Gastrectomy for Gastric Cancer

Guner A, Kim KY, Park SH, Cho M, Kim YM, Hyung WJ, Kim HI

Purpose: This study aimed to investigate the relationship between clinical and laboratory parameters and complication status to predict which patients can be safely discharged from the hospital on the third...
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Tumor Location Causes Different Recurrence Patterns in Remnant Gastric Cancer

Sun B, Zhang H, Wang J, Cai H, Xuan Y, Xu D

Purpose: Tumor recurrence is the principal cause of poor outcomes in remnant gastric cancer (RGC) after resection. We sought to elucidate the recurrent patterns according to tumor locations in RGC. Materials...
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Urinary Biomarkers for the Noninvasive Detection of Gastric Cancer

Li D, Yan L, Lin F, Yuan X, Yang X, Yang X, Wei L, Yang Y, Lu Y

Gastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC...
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Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner

Choi YS, Cho HJ, Jung HJ

Gastric cancer stem cells (GCSCs) are a major cause of radioresistance and chemoresistance in gastric cancer (GC). Therefore, targeting GCSCs is regarded as a powerful strategy for the effective treatment...
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Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy

Fujisaki M, Nomura T, Yamashita H, Uenosono Y, Fukunaga T, Otsuji E, Takahashi M, Matsumoto H, Oshio A, Nakada K

Purpose: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based...
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Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening to Helicobacter pylori Eradication in Korea

Kim YI, Choi IJ

Gastric cancer is prevalent in Korea and ranked as the third most common cancer in 2019, followed by lung and thyroid cancers. The National Cancer Screening Program (NCSP) for gastric...
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Epidemiology of Gastric Cancer in Korea: Trends in Incidence and Survival Based on Korea Central Cancer Registry Data (1999–2019)

Park SH, Kang MJ, Yun EH, Jung KW

This study investigated the trends of gastric cancer in Korea by adding the latest updated gastric cancer data from 2019. Gastric cancer incidence between 1999 and 2019 was reviewed using...
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Paneth Cell Carcinoma of the Stomach

Kim JW, Kim GH, Kim KB

Paneth cell carcinoma is a rare carcinoma composed predominantly or purely of malignant Paneth cells. An 83-year-old woman presented for evaluation of an elevated lesion in the stomach. On endoscopy,...
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Convenience of Adding a Needle Grasper in Single-Incision Laparoscopic Distal Gastrectomy With Billroth I Anastomosis for Clinical Early Gastric Cancer

Kim JW, Park JM, Chi KC

Purpose: To overcome the technical difficulties of single-incision laparoscopic distal gastrectomy (SILDG), needle grasper (Endo Relief TM )-assisted SILDG (NASILDG) was developed. Here, we compared the operative convenience and postoperative...
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Establishment of Patient-Derived Gastric Cancer Organoid Model From Tissue Obtained by Endoscopic Biopsies

Song H, Park JY, Kim JH, Shin TS, Hong SA, Huda MN, Kim BJ, Kim JG

Cancer organoids are three-dimensional mini-organ analogues derived from cancer tissues and have been proposed as models capable of simulating the structure and function of human organs and tissues in vitro....
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The Clinical Impact of Advanced Age on the Postoperative Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Analysis Across US Hospitals Between 2011–2017

Lee DU, Fan GH, Chang K, Lee KJ, Han J, Jung D, Kwon J, Karagozian R

Purpose: This study systematically evaluated the implications of advanced age on postsurgical outcomes following gastrectomy for gastric cancer using a national database. Materials and Methods: The 2011–2017 National Inpatient Sample was...
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