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Rituximab plus multiagent chemotherapy for newly diagnosed CD20-positive acute lymphoblastic leukemia: a prospective phase II study

Baek DW, Park HS, Sohn SK, Kim DY, Kim I, Ahn JS, Do YR, Lee SR, Eom HS, Lee WS, Kim SH, Lee HS, Lee YJ, Moon JH, Lee JH, Adult Acute Lymphoblastic Leukemia Working Party, the Korean Society of Hematology

Background/Aims: We performed a prospective study to determine the efficacy and safety of rituximab including chemotherapy in CD20-positive acute lymphoblastic leukemia (ALL). Methods: Patients with newly diagnosed ALL, aged ≥ 15...
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Scrub typhus infection in a kidney transplant recipient: a case report

Lee D, Jeon J, Ahn JS, Baek CH

Scrub typhus is a febrile disease that is endemic to Asia and the Pacific region. Its clinical manifestations include fever, myalgia, lymphadenopathy, and a characteristic eschar. The main manifestations of...
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A Case of Aphasic Seizure as a Manifestation of Nonketotic Hyperglycemia in a Patient Undergoing Peritoneal Dialysis

Ahn JS, Lee D, Jeon J, Ryu JC, Chang JW

Peritoneal glucose absorption in peritoneal dialysis causes hyperglycemia. Nonketotic hyperglycemia (NKH) includes hyperosmolar hyperglycemic state, which refers to a condition that includes hyperglycemia, hyperosmotic pressure, and dehydration without severe acidosis....
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The prognostic impact of reduced variant burden in elderly patients with acute myeloid leukemia treated with decitabine

Kim M, Kim T, Ahn SY, Lee JH, Park JH, Shin MG, Jung SH, Song GY, Yang DH, Lee JJ, Choi SH, Kim MY, Ahn JS, Kim HJ, Kim DDH

Background/Aims: We evaluated the role of next-generation sequencing (NGS)-based disease monitoring for elderly patients diagnosed with acute myeloid leukemia (AML) who received decitabine therapy. Methods: A total of 123 patients aged...
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Improvement in Dasatinib-Induced Proteinuria after Switching to Nilotinib: A Case Report

Jeon J, Lee D, Ahn JS, Baek CH, Kim H

Tyrosine kinase inhibitors (TKIs), such as imatinib, dasatinib, and nilotinib, have been used to treat chronic myelogenous leukemia (CML). The adverse effects of these TKIs vary according to the site...
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Efficacy of intraoperative neuromonitoring (IONM) and intraoperative indocyanine green videoangiography (ICG-VA) during unruptured anterior choroidal artery aneurysm clipping surgery

Eun C, Lee SJ, Park JC, Ahn JS, Kwun BD, Park W

Objective: The aim of this study was to investigate the efficacy of intraoperative indocyanine green videoangiography (ICG-VA) and intraoperative neuromonitoring (IONM) to prevent postoperative ischemic complications during microsurgical clipping of...
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Efficacy of Acetylcysteine and Selenium in Aneurysmal Subarachnoid Hemorrhage Patients: A Prospective, Multicenter, Single Blind Randomized Controlled Trial

Kim M, Jeon H, Chung Y, Lee SU, Park W, Park JC, Ahn JS, Lee S

Background: Subarachnoid hemorrhage (SAH) patients have oxidative stress results in inflammation, tissue degeneration and neuronal damage. These deleterious effects cause aggravation of the perihematomal edema (PHE), vasospasm, and even hydrocephalus....
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Effect of hemispherical dimples at titanium implant abutments for the retention of cemented crowns

Choi JH, Heo SJ, Koak JY, Kim SK, Park JM, Ahn JS

PURPOSE. The aim of this study was to assess the effect of hemispherical dimple structures on the retention of cobalt–chromium (Co–Cr) crowns cemented to titanium abutments, with different heights and...
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Prognostic Impact of Elevation of Cancer Antigen 15-3 (CA15-3) in Patients With Early Breast Cancer With Normal Serum CA15-3 Level

Ryu JM, Kang D, Cho J, Lee JE, Kim SW, Nam SJ, Lee SK, Kim YJ, Im YH, Ahn JS, Park YH, Kim JY, Lee H, Kang M, Yu JH

Purpose: Cancer antigen 15-3 (CA15-3) is a serum tumor marker for breast cancer (BC) extensively used in clinical practice. CA15-3 is non-invasive, easily available, and a costeffective tumor marker for...
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The Role of Brain Radiotherapy before First-Line Afatinib Therapy, Compared to Gefitinib or Erlotinib, in Patients with EGFR-Mutant Non–Small Cell Lung Cancer

Jung HA, Park S, Lee SH, Ahn JS, Ahn MJ, Sun JM

Purpose Brain metastasis is common in patients with epidermal growth factor receptor (EGFR)–mutant non–small cell lung cancer (NSCLC) at initial presentation. A previous study showed that brain radiotherapy (RT) before...
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A Phase II Trial of S-1 and Oxaliplatin in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and Taxane (KCSG-BR07-03)

Lee DW, Keam B, Lee KS, Ahn JH, Sohn J, Ahn JS, Lee MH, Kim JH, Lee KE, Kim HJ, Kim SY, Park YH, Ock CY, Lee KH, Han SW, Kim SB, Im YH, Chung HC, Oh DY, Im SA

Purpose This single-arm phase II trial investigate the efficacy and safety of S-1 plus oxaliplatin (SOX) in patients with metastatic breast cancer. Materials and Methods Patients with metastatic breast cancer previously...
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EGFR Mutation–Positive Unresectable Stage III Non-Squamous Lung Cancer Is Associated with a High Incidence of Brain Metastasis

Kim H, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Ahn MJ

Purpose The impact of epidermal growth factor receptor (EGFR) mutation in locally advanced non–small cell lung cancer (NSCLC) remains controversial. This study was conducted to investigate the clinical outcomes and...
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Pseudoaneurysm formation or dural arteriovenous fistula formation at the middle meningeal artery following revascularization surgery in Moyamoya disease

Seo D, Yoon BH, Byun J, Park W, Park JC, Ahn JS

Moyamoya disease (MMD) is a rare progressive steno-occlusive cerebrovascular disorder. Currently, revascularization surgery is used as optimal treatment to overcome MMD. However, revascularization for MMD has reported several complications. Also,...
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Clinical Experience of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients Aged 60 Years and Older in South Korea

Ji YS, Ahn JS, Yun J, Jang GH, Lim SH, Kim SH, Kim CK, Won JH, Park SK

Purpose: The purpose of this study is to share our outcomes and experiences on allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients aged 60 years and older with myelodysplastic...
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Five-Year Overall Survival and Prognostic Factors in Patients with Lung Cancer: Results from the Korean Association of Lung Cancer Registry (KALC-R) 2015

Jeon DS, Kim HC, Kim SH, Kim TJ, Kim HK, Moon MH, Beck KS, Suh YG, Song C, Ahn JS, Lee JE, Lim JU, Jeon JH, Jung KW, Jung CY, Cho JS, Choi YD, Hwang SS, Choi CM, Korean Association for Lung Cancer, Korea Central Cancer Registry

Purpose This study aimed to provide the clinical characteristics, prognostic factors, and 5-year relative survival rates of lung cancer diagnosed in 2015. Materials and Methods The demographic risk factors of lung...
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Osimertinib Combined with Systemic Chemotherapy for EGFR Mutant, T790M-Negative, Non–Small Cell Lung Cancer Patients Who Develop Leptomeningeal Metastases with Extracranial Progression to Prior EGFR TKI

Kim HR, Jo H, Kim H, Hong J, Park S, Jung HA, Lee SH, Ahn JS, Ahn MJ

Leptomeningeal metastasis (LM) is a rare but fatal clinical condition with a short survival time. The incidence of LM from epidermal growth factor receptor mutant (EGFRm) non–small cell lung cancer...
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Analysis of surface characteristics of (Y, Nb)-TZP after finishing and polishing

Yoo Sk, Jo YH, Yeo ISL, Yoon HI, Lee JH, Ahn JS, Han JS

PURPOSE. This in vitro study aimed to evaluate the surface characteristics of a full veneer crown fabricated chairside (CS) from a (Y, Nb)-TZP zirconia block in response to conventional zirconia...
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Evaluation of MET alteration in EGFR-mutant non-small cell lung cancer patients treated with EGFR tyrosine kinase inhibitor from paired biopsy: A retrospective cohort study

Ku BM, Park S, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Choi YL, Ahn MJ

Purpose: Mesenchymal-epithelial transition tyrosine kinase receptor (MET) amplification is one of the common acquired resistance mechanisms to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). To evaluate the usefulness...
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Validity and reproducibility of a food frequency questionnaire for breast cancer survivors in Korea

Moon SE, Shin Wk, Song S, Koh D, Ahn JS, Yoo Y, Kang M, Lee JE

BACKGROUND/OBJECTIVES: The aim of this study was to examine the validity and reproducibility of a food frequency questionnaire (FFQ) developed in Korea for breast cancer survivors. SUBJECTS/METHODS: Ninety-nine breast cancer survivors...
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In vivo imaging of renal microvasculature in murine ischemia-reperfusion injury models using optical coherence tomography angiography

Cho JH, Oh SH, Kim YJ, Ahn JS, Yook JM, Oh EJ, Lee B, Kang W, Oh WY

Background: Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique that provides three-di-mensional structural and semi-quantitative imaging of the microvasculature in vivo. We developed an OCTA imaging protocol for...
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