Korean J Med Mycol.  2013 Sep;18(3):70-75.

Localized Skin Infection Caused by Fusarium oxysporum

• Lee MH
• Yoo JY
• Song YB
• Suh MK
• Ha GY
• Lee JI
• Lee HJ

Abstract

Fusarium(F.) species are hyalohyphomycetes isolated from plants, soil and air. Fusarium species can cause disseminated infections with involvement of multiple organs and numerous skin lesions in immunocompromised patients. And they can also cause local skin infections of trauma site. We report a case of localized skin infection by F. oxysporum in a 63-year-old immunocompetent woman. She presented with multiple, mild pruritic, 1.5 x 1.5 cm-sized, erythematous maculopapules on the left cheek after cosmetic procedure 4 months ago. Histopathologically, suppurative granulomatous inflammation, fungal elements were observed in dermis. Fungal culture on Sabouraud's dextrose agar showed rapid growing, whitish, cottony colonies at 25degrees C for 1 week. Numerous fusoid macroconidia were observed in slide culture by light microscopy. The nucleotide sequences of the internal transcribed spacer (ITS) region of clinical sample identical to that of F. oxysporum CID 220 strain (GenBank accession number HQ829117.1). The patient had been treated with itraconazole for 6 months. The skin lesion was improved. There was no recurrence 6 months after treatment.

Keyword

Fusarium oxysporum; Localized skin infection

MeSH Terms

Agar
Base Sequence
Cheek
Dermis
Female
Fusarium*
Glucose
Humans
Immunocompromised Host
Inflammation
Itraconazole
Microscopy
Middle Aged
Recurrence
Skin*
Soil
Wounds and Injuries
Agar
Glucose
Itraconazole
Soil