Korean J Med Mycol.
2000 Mar;5(1):24-30.
A Case of Disseminated Cutaneous Infection Caused by Fusarium oxysporum in an Immunocompromised Patient
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- 2Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- With the wide and extensive use of immunosuppressive agents and broad-spectrum antibiotics, opportunistic fungla infections have been increased. Fusarium spp. are known to be significant emerging pathogens of opporthunistic local infection. But very rarely it may cause fatalc systemic infection. A 4-year-old boy with acute lymphocytic leukemia develped asymptomatic disseminated purpura with high fever unresponsive to the antibiotics during chemotherapy. The skin lesions gradually increased in size and number, and prgreassed to forming central necrosis. Many septated hyphae and variable sized spore-like fungal elements are found in the epidrmis, dermis and subcuit on histologic sections. The pathogenic fungus was idenified as Fusarium oxysporum by culture and scanning electronic microscopic findings.
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