Study on Serum and Urinary Levels of Calcium, Inorganic Phosphorus and Uric Acid in Patients with Urinary Stone and Immobilized State

Yim, Cheol Soon; Chang, Dae Soo

Abstract

The serum concentration and urinary excretion of calcium, inorganic phosphorus and uric acid in 75 stone-former and 33 immobilized patients, comparing to those in 45 controls . The following results were obtained. 1. Serum calcium levels of stone-formers were significantly higher than those of controls in total, male and female. 2. Urinary calcium levels of stone-formers were significantly higher than those of controls in total and female, but not in male. 3. Serum and urinary levels of inorganic phosphorus did not show significant difference between stoneformers and controls. 4. Serum and urinary levels of uric acid in stone-formers were significantly higher than those of controls in total, male and female. 5. Serum and urinary levels of calcium in immobilized patients were higher than those of controls, but did not show significant difference between both groups. 6. Serum and urinary levels of inorganic phosphorus in immobilized patients were slight higher than those of controls, but did not show significant difference between both groups. 7. Serum and urinary uric acid levels of immobilized patients were lower than those of controls, but showed significant difference between both groups only in urinary uric acid levels. These results suggest the possibility that increased calcium and uric acid level may play some role in the genesis of urinary stone. Urinary uric acid level significantly decrease in immobilized state.