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The Uric Acid and Gout have No Direct Causality With Osteoarthritis: A Mendelian Randomization Study

Lee YH, Song GG

OBJECTIVE: To examine whether uric acid level or gout is causally associated with the risk of osteoarthritis. METHODS: We performed a two-sample Mendelian randomization (MR) analysis using inverse-variance weighted (IVW), MR-Egger...
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What is the Best Choice for Urate-lowering Therapy for Korean?

Cheon YH, Song JS

Gout is one of the most common forms of acute inflammatory arthritis caused by long-standing hyperuricemia. Various clinical and epidemiological studies have demonstrated that uric acid, which is strongly associated...
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Serum and Urine Uric Acid as a Biomarker in Osteoarthritis

Jun JB

No abstract available.
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Hyperuricemia Is Not Predictive of Long-Term Outcome in Patients with Stable Chronic Obstructive Pulmonary Disease

Hwang JJ, Oh YM, Rhee CK, Yoo KH, Park YB, Yoon HI, Lim SY, Lee JH, Kim EK, Kim TH, Lee SW, Lee SD, Lee JS, KOLD Group

BACKGROUND: Although the association of hyperuricemia with an increased risk of mortality has been demonstrated in the context of acute exacerbation of chronic obstructive pulmonary disease (COPD), the long-term outcomes...
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Clinical Usefulness of Uric Acid as a Biomarker for Knee Osteoarthritis: A Comparative Analysis With Plain Radiography and Musculoskeletal Ultrasound

Kim SK, Jung UH, Choe JY

OBJECTIVE: The aim of this study was to determine the relationships of serum and urine uric acid with severity or activity in knee osteoarthritis (OA). METHODS: A total of 42 patients...
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Paroxysmal Seizure-Like Activities Caused by Unrecognized Acute Myocarditis Masquerading as Febrile Seizures in Children

Jeong SH, Nam SO, Lee HD, Park JA, Byun SY, Ko H, Ko A, Kong J, Kim YM, Lee YJ

PURPOSE: Recognition of cardiogenic syncope caused by acute myocarditis masquerading as febrile seizures (FS) in children can be difficult in the emergency department (ED) before a cardiac work-up. We aimed...
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Investigation of the effect of coffee on body weight, serum glucose, uric acid and lipid profile levels in male albino Wistar rats feeding on high-fructose diet

Feyisa TO, Melka DS, Menon M, Labisso WL, Habte ML

Coffee is one of the most commonly consumed beverages in the worldwide and is assumed to have protective effects against metabolic syndrome. The present study was aimed at investigating the...
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Protective effects of D-005, a lipid extract from Acrocomia crispa fruits, against ischemia/reperfusion-induced acute kidney injury in rats

Oyarzábal-Yera A, Rodríguez-Salgueiro S, Merino-García N, Ocaña-Nápoles L, González-Núñez L, Mena-Valdés L, Zamora-Rodríguez Z, Medina-Pírez JA, Jiménez-Despaigne S, Molina-Cuevas V

BACKGROUND: Acute kidney injury (AKI) induced by renal ischemia/reperfusion (IR) is associated with enhanced production of reactive oxygen species in renal tissues. D-005, a lipid extract obtained from Acrocomia crispa...
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The Relationship between Pulmonary Function and Serum Uric Acid Level in the Korean Population

Kim GT, Sull JW

BACKGROUND: Forced vital capacity (FVC), forced expiratory volume in the first second (FEV₁), and the ratio of FEV₁ to FVC (FEV₁/FVC) are considered as the major spirometry parameters. Serum uric...
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Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity

Özcabı B, Demirhan S, Akyol M, Öztürkmen Akay H, Güven A

BACKGROUND: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. PURPOSE: Here we evaluated the ability of LAP to predict NAFLD...
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Baseline High Blood Pressure is Associated with Clinico-Pathologic Findings and Later Renal Progression in Chronic Glomerulonephritis

Lee JY, Ihm HS, Kim JS, Hwang HS, Jeong KH, Ihm CG

BACKGROUND: Several factors had been suggested to contribute to the development of hypertension in chronic glomerulonephritis (GN). This study was conducted to find the association of baseline blood pressure (BP)...
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Serum Uric Acid and Metabolic Syndrome: a Retrospective Cohort Study

Kim HS

No abstract available.
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Association between Serum Uric Acid and Metabolic Syndrome in Koreans

Jeong J, Suh YJ

BACKGROUND: Although previous studies have highlighted the importance of serum uric acid as a risk factor of metabolic syndrome, no study has previously used a national Korean survey to examine...
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Elevated Serum Uric Acid in Benign Convulsions with Mild Gastroenteritis in Children

Yoo IH, Kim W, Cho J, Kim H, Lim BC, Hwang H, Chae JH, Choi J, Kim KJ

BACKGROUND AND PURPOSE: To identify whether serum uric acid levels are significantly higher in patients with benign convulsion associated with mild gastroenteritis (CwG) than in patients with acute gastroenteritis. METHODS: This...
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A Putative Adverse Outcome Pathway Relevant to Carcinogenicity Induced by Sulfuric Acid in Strong Inorganic Acid Mists

Yang JH, Koedrith P, Kang DS, Kee NK, Jung JH, Lee CM, Ahn YS, Seo YR

Based on epidemiological studies, an International Agency for Research on Cancer Working Group determined that strong inorganic acid mists containing sulfuric acid are carcinogenic to human even though, sulfuric acid,...
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The roles of triglyceride/high-density lipoprotein cholesterol ratio and uric acid as predisposing factors for metabolic syndrome in healthy children

Katsa ME, Ioannidis , Sachlas A, Dimopoulos I, Chatzipanagiotou S, Rojas Gil

PURPOSE: To estimate the roles of triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio and uric acid in predisposition for metabolic syndrome (MetS) and its components in healthy children. METHODS: Anthropometric and biochemical analyses...
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Increased Carotid Intima-Media Thickness (IMT) in Hyperuricemic Individuals May Be Explained by Hyperhomocysteinemia Associated with Renal Dysfunction: a Cross-Sectional Study

Park JH, Song JS, Choi ST

BACKGROUND: Both hyperuricemia and hyperhomocysteinemia are known as main risk factors of cardiovascular diseases. There has been, however, no report on the relationship between carotid intima-media thickness (IMT) and homocysteine...
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Physicians' perceptions of asymptomatic hyperuricemia in patients with chronic kidney disease: A questionnaire survey

Cha RH, Kim SH, Bae EH, Yu M, Choi BS, Choi HY, Kang SW, Shin J, Han SY, Yang CW, Kang DH

BACKGROUND: Hyperuricemia is associated with the development and progression of chronic kidney disease (CKD) as well as cardiovascular diseases. However, there is no consistent recommendation regarding the treatment of asymptomatic...
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Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease

D'Marco L, Salazar J, Cortez M, Salazar M, Wettel M, Lima-Martínez M, Rojas E, Roque W, Bermúdez

BACKGROUND: Adipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function and...
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Proximal renal tubular acidosis with and without Fanconi syndrome

Kashoor I, Batlle D

Proximal renal tubular acidosis (RTA) is caused by a defect in bicarbonate (HCO₃⁻) reabsorption in the kidney proximal convoluted tubule. It usually manifests as normal anion-gap metabolic acidosis due to...
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