J Korean Rheum Assoc.  1995 Jan;2(1):60-68.

Serum Uric Acid Levels In Korean Adult Population And Their Correlates

Affiliations
  • 1Devision of Clinical Immunology, Asan Medical Center, College of Medicine, Ulsan University, Seoul, Korea.

Abstract


OBJECTIVE
To investigate the distribution of serum uric acid levels among 20000 Korean people who visited health screening center and relationships between serum uric acid and a number of biological variables.
METHODS
By descriptive analysis on obesity index, blood pressures and various chemical measurements. Serum uric acid levels were measured by uricase method. Stepwise regression analysis of serum uric acid levels on various host variables selected on the basis of univariate analysis was perfomed. Logistic regression analysis was performed for the odds ratios for hyperuricemia.
RESULTS
The mean serum uric acid level and prevalence of hyperuricemia were 5.9+/-1.3 mg/dl, 16.6% respectively in men and 4.2+/-l.0mg/dl, 1.69% in women. Serum creatinine concentration was by far the most important correlate with serum uric acid level. Obesity index, serum calcium, triglycerid were also significantly associated with serum uric acid in both sexes. Contributing factors for hyperuricema were calcium, serum GPT and obesity index in both sexes, and serum trig]yceride level, age, hypertension in men only.
CONCLUSIONS
The mean serum uric acid level in men is higher than in women throughout all ages and the uric acid level arised after 5th decade in women. There are differences in contributing factors for serum uric acid level between sexes as well as in risk factor for hyperuricemia.

Keyword

Uric acid; Hyperuricemia; Epidemiology; Risk factor

MeSH Terms

Adult*
Calcium
Creatinine
Epidemiology
Female
Humans
Hypertension
Hyperuricemia
Logistic Models
Male
Mass Screening
Multiple Endocrine Neoplasia Type 1
Obesity
Odds Ratio
Prevalence
Risk Factors
Urate Oxidase
Uric Acid*
Calcium
Creatinine
Urate Oxidase
Uric Acid
Full Text Links
  • JKRA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr