Korean J Anesthesiol.  2006 Jun;50(6):S68-S70. 10.4097/kjae.2006.50.6.S68.

Severe Oropharyngeal Angioedema Caused by Propofol: A case report

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Ulsan University School of Medicine, Ulsan, Korea. gamju@yahoo.co.kr
  • 2Department of Oral & Maxillofacial Surgery, Ulsan University School of Medicine, Ulsan, Korea.
  • 3Department of Internal Medicine, Ulsan University School of Medicine, Ulsan, Korea.

Abstract

Although propofol is thought to be a relatively safe intravenous anesthetic with regard to histamine release reactions, anaphylactoid reactions to propofol may sometimes occur, especially in patients with a history of allergy, atopy, or asthma. Here we report a patient with allergies to sesame leaves and cold medications who experienced an anaphylactic reaction with severe oropharyngeal edema a few minutes after receiving propofol (Anepol(R)). This finding suggests that propofol should be used with caution in patients with a history of allergy. Because profound airway edema can occur, the airway should be evaluated before extubation of the trachea.

Keyword

airway; anaphylactic reaction; oropharyngeal edema; propofol

MeSH Terms

Anaphylaxis
Angioedema*
Asthma
Edema
Histamine Release
Humans
Hypersensitivity
Propofol*
Sesamum
Trachea
Propofol
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