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The effect of hypothalamic involvement and growth hormone treatment on cardiovascular risk factors during the transition period in patients with childhood-onset craniopharyngioma

Park SH, Lee YJ, Cheon JE, Shin CH, Jung HW, Lee YA

Purpose: Hypothalamic damage may increase the risk of adulthood obesity and cardiovascular disease in patients with craniopharyngioma. We evaluated the effects of hypothalamic involvement (HI) and growth hormone (GH) discontinuation...
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A Case of Empty Nose Syndrome Developed After Septal Spur Removal

Shin CH, Jang YJ

Empty nose syndrome (ENS) is a rare complication of turbinate surgery, in which patients suffer from symptoms such as paradoxical nasal obstruction, nasal dryness, facial pain and feeling excessive nasal...
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Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer

Choe Y, Lee YJ, Shin CH, Chung EJ, Lee YA

Purpose: Hypoparathyroidism (hypoPTH) is the most common complication following thyroidectomy. We investigated the frequency and risk factors of hypoPTH after total thyroidectomy (TT) in pediatric patients with thyroid cancer. Methods: This...
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Relationship Between the Serum FGF21 Level and Growth in Children of Short Stature

Lee YJ, Jung SY, Lee YA, Kim J, Lee SY, Shin CH

Background: This study investigated the relationship between fibroblast growth factor 21 (FGF21) levels and growth in children with growth hormone deficiency (GHD) and idiopathic short stature (ISS), and the effects...
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Glutamic Acid Decarboxylase and Tyrosine Phosphatase-Related Islet Antigen-2 Positivity among Children and Adolescents with Diabetes in Korea

Kim KY, Kim MS, Lee YJ, Lee YA, Lee SY, Shin CH, Kim JH

Autoantibodies against glutamic acid decarboxylase (GADA), tyrosine phosphatase-related islet antigen 2 (IA2A), insulin (INSA), and islet cells (ICA) are critical for determining the type of diabetes and management strategy in...
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Cerebrotendinous xanthomatosis in a 10-year-old male presenting with Achilles tendon xanthoma and mild intellectual disability: A case report

Yoon JH, Kim KY, Lee SY, Kim SY, Lee YA, Ki CS, Song J, Shin CH, Lee YJ

Cerebrotendinous xanthomatosis (CTX) is a rare genetic disease caused by a deficiency of enzymes for the synthesis of bile acid, resulting in the accumulation of cholestanol with reduced chenodeoxycholic acid...
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Impact of COVID-19 Pandemic on Pediatric Diabetes Mellitus

Shin CH

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Metabolic Impacts of Discontinuation and Resumption of Recombinant Human Growth Hormone Treatment during the Transition Period in Patients with Childhood-Onset Growth Hormone Deficiency

Lee YJ, Choi Y, Yoo HW, Lee YA, Shin CH, Choi HS, Kim HS, Kim JH, Moon JE, Ko CW, Ahn MB, Suh BK, Choi JH

Background: Discontinuing growth hormone (GH) treatment during the transition to adulthood has been associated with adverse health outcomes in patients with childhood-onset growth hormone deficiency (CO-GHD). This study investigated the...
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Effects of circadian blood pressure patterns on development of microvascular complications in pediatric patients with type 1 diabetes mellitus

Lee JS, Lee YJ, Lee YA, Shin CH

Purpose: The effects of circadian blood pressure (BP) alterations on the development and progression of microvascular complications in type 1 diabetes mellitus (T1DM) patients are unknown. We evaluated the effects...
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Effects of taurine and ginseng extracts on energy metabolism during exercise and their anti-fatigue properties in mice

Kim J, Beak S, Ahn S, Moon BS, Kim BS, Lee SJ, Oh SJ, Park HY, Kwon SH, Shin CH, Lim K, Lee KP

BACKGROUND/OBJECTIVES: Ginseng extract (GSE) and taurine (TR) are widely used antifatigue resources in functional foods. However, the mechanism underlying the antifatigue effects of GSE and TR are still unclear. Hence,...
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History of insulin treatment of pediatric patients with diabetes in Korea

Kim JH, Shin CH, Yang SW

The year 2021 is the centennial of insulin discovery. The discovery of insulin changes diabetes mellitus from a death sentence to a manageable disease. It became a historical turning point...
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Impact of the COVID-19 Pandemic on the Diagnosis and Surgery of Breast Cancer: A Multi-Institutional Study

Kang YJ, Baek JM, Kim YS, Jeon YW, Yoo TK, Rhu J, Shin CH, Cho S, Choi H, Oh SJ

Purpose: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted the rates of screening, case identification, and referral for cancer diagnosis. We investigated the diagnosis and surgery status of breast...
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Septodermoplasty: Make It Easier

Shin CH, Jang YJ

Septodermoplasty (SDP) is a technique that presents a surgical option for the treatment of recalcitrant epistaxis from hereditary hemorrhagic telangiectasia. It involves the removal of affected nasal epithelium, replacing it...
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Nasal Floor Slanting and Its Association With Nasofacial Structures

Park MJ, Choi Y, Shin CH, Jang YJ

Background and Objectives Nasal floor slanting (NFS) is an incidental radiographic finding of asymmetry in the nasal floor level. Despite its frequent appearance, however, NFS has never been properly defined,...
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Maternal Hyperglycemia during Pregnancy Increases Adiposity of Offspring

Chung HR, Moon JH, Lim JS, Lee YA, Shin CH, Hong JS, Kwak SH, Choi SH, Jang HC

Background: The effect of intrauterine hyperglycemia on fat mass and regional fat proportion of the offspring of mothers with gestational diabetes mellitus (OGDM) remains to be determined. Methods: The body composition...
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Clinical Application of Sequential Epigenetic Analysis for Diagnosis of Silver–Russell Syndrome

Kim SY, Shin CH, Lee YA, Shin CH, Yang SW, Cho TJ, Ko JM

Background: Silver-Russell syndrome (SRS) is a pre- or post-natal growth retardation disorder caused by (epi)genetic alterations. We evaluated the molecular basis and clinical value of sequential epigenetic analysis in pediatric...
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Associations Between Thyroid Hormone Levels and Urinary Concentrations of Bisphenol A, F, and S in 6-Year-old Children in Korea

Jang Y, Choi YJ, Lim YH, Lee KS, Kim BN, Shin CH, Lee YA, Kim JI, Hong YC

Objectives: Bisphenol A (BPA) is used in the electrical, mechanical, medical, and food industries. Previous studies have suggested that BPA is an endocrine disruptor. Regulation of BPA has led to...
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The durability and effectiveness of sensor-augmented insulin pump therapy in pediatric and young adult patients with type 1 diabetes

Lee YJ, Lee YA, Kim JH, Chung HR, Gu MJ, Kim JY, Shin CH

Purpose: Despite the prevalent use of insulin pump therapy worldwide, few studies have been conducted among young patients with type 1 diabetes (T1D) in Korea. We investigated the durability and...
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Management of Osteogenesis Imperfecta: A Multidisciplinary Comprehensive Approach

Cho TJ, Ko JM, Kim H, Shin HI, Yoo WJ, Shin CH

Osteogenesis imperfecta (OI) is characterized by recurring fractures and limb and spine deformities. With the advent of medical therapeutics and the discovery of causative genes, as well as the introduction...
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Managing Complicated Diabetic Foot Ulcers with Peripheral Arterial Disease

Yu SH, Kim DC, Shin CH

Background: Diabetic foot ulcers are an issue of clinical interest as diabetes has become the leading cause of occlusive vasculopathy. The purpose of this study is to evaluate the clinical...
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