Diabetes Metab J.  2011 Oct;35(5):504-512. 10.4093/dmj.2011.35.5.504.

Prevalence of Chronic Complications in Korean Patients with Type 2 Diabetes Mellitus Based on the Korean National Diabetes Program

Affiliations
  • 1Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea. kimys@khmc.or.kr
  • 2Research Institute of Endocrinology, Kyung Hee University, Seoul, Korea.
  • 3Department of Endocrinology, Gachon University of Science and Medicine, Incheon, Korea.
  • 4Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
  • 5Division of Endocrinology and Metabolism, Department of Medicine, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
  • 6Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
  • 7Department of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
  • 8Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.
  • 9Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 10Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
  • 11Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
  • 12Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.

Abstract

BACKGROUND
The Korean National Diabetes Program (KNDP) cohort study is performing an ongoing large-scale prospective multicenter investigation to discover the pathogenesis of type 2 diabetes in Korean patients. This study was performed to examine the prevalence of chronic complications in patients with type 2 diabetes among those registered in the KNDP cohort within the past 4 years.
METHODS
This study was performed between June 2006 and September 2009 at 13 university hospitals and included 4,265 KNDP cohort participants. Among the participants, the crude prevalence of microvascular and macrovascular diseases of those checked for diabetes-related complications was determined, and the adjusted standard prevalence and standardization of the general population prevalence ratio (SPR) was estimated based on the 2005 Korean National Health and Nutrition Examination Survey (KNHANES) population demographics.
RESULTS
Among the KNDP registrants, 43.2% had hypertension, 34.8% had dyslipidemia, 10.8% had macrovascular disease, and 16.7% had microvascular disease. The SPR of the KNDP registrants was significantly higher than that of the KNHANES subjects after adjusting for demographics in the KNHANES 2005 population. However, with the exception of cardiovascular disease in females, the standardized prevalence for the most complicated items in the survey was significantly higher than that in the KNHANES subjects.
CONCLUSION
The prevalence of macrovascular disease and peripheral vascular disease were significantly higher in Korean patients with type 2 diabetes than in the normal population. However, no significant difference was noted in the prevalence of cardiovascular disease in females.

Keyword

Cerebrovascular disorders; Coronary disease; Diabetes mellitus, type 2; Diabetic retinopathy; Korea

MeSH Terms

Cardiovascular Diseases
Cerebrovascular Disorders
Cohort Studies
Coronary Disease
Demography
Diabetes Complications
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Dyslipidemias
Female
Hospitals, University
Humans
Hypertension
Korea
Nutrition Surveys
Peripheral Vascular Diseases
Prevalence
Prospective Studies

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