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Dietary nobiletin suppresses TGF-β1-Src-caveolin-1 dependent signaling involved with high glucose-induced renal mesangial matrix accumulation

Kim DY, Kang YH, Kang MK

PURPOSE: Diabetic nephropathy is one of the most important diabetic complications prompted by chronic hyperglycemia, characterized by glomerulosclerosis, tubular fibrosis, and it eventually causes kidney failure. Nobiletin is a polymethoxyflavone...
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Impact of Continuous Care on Health Outcomes and Cost for Type 2 Diabetes Mellitus: Analysis Using National Health Insurance Cohort Database

Nam JH, Lee C, Kim N, Park KY, Ha J, Yun J, Shin DW, Shin E

BACKGROUND: The objective of the study was to determine the impact of continuous care on health outcomes and cost of type 2 diabetes mellitus (T2DM) in Korea. METHODS: A nationwide retrospective,...
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Review of Diabetic Foot Complication Assessment Tools Developed from 2007 to 2016

Lee Y, Song Y

PURPOSE: The purpose of this study was to analyze the attributes and psychometric properties of newly developed diabetic foot complication assessment tools. The attributes of diabetic foot complication assessment tools...
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Association between Diabetes and the Use of Removable Dental Prostheses among the Korean Population

Lee JH, Han JS, Han K, Lee SY

BACKGROUND: A balanced nutrient intake is important for patients with diabetes. Even if individuals have the same number of residual natural teeth, there are large differences in the masticatory performance...
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The Role of Anti-Obesity Medication in Prevention of Diabetes and Its Complications

Oh TJ

Diabetes is prevalent in obese population, and obesity management is the first step in preventing diabetes. Traditionally, lifestyle modification including reduced-calorie diet, physical activity, and behavior intervention is the core...
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Comprehensive Management in Patients with Type 2 Diabetes Mellitus

Kim SK

Management of patients with diabetes mellitus should not be restricted to the treatment of hyperglycemia and diabetic complications. An integrated comprehensive approach is needed for successful management, which should include...
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Risk Factors Management in Diabetic Patients

Kim SY

Diabetes mellitus is associated with a high frequency of complications related to cardiovascular disease as well as microvascular complications such as nephropathy, retinopathy, and neuropathy. Prevention of these vascular complications...
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Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea

Seo DH, Kang S, Lee YH, Ha JY, Park JS, Lee BW, Kang ES, Ahn CW, Cha BS

BACKGROUND: This study investigated the overall status of diabetes control and screening for diabetic microvascular complications in patients with type 2 diabetes mellitus attending primary care clinics in Korea. METHODS: In...
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Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective

Rhee EJ

Nonalcoholic fatty liver disease (NAFLD) is thought to stem from the body's inability to store excess energy in adipocytes; as such, it is commonly viewed as the hepatic manifestation of...
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Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia

Ly H, Despa F

Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent...
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Effect of Dipeptidyl Peptidase-4 Inhibitors on the Risk of Bone Fractures in a Korean Population

Ustulin M, Park SY, Choi H, Chon S, Woo JT, Rhee SY

BACKGROUND: There have been equivocal results in studies of the effects of dipeptidyl peptidase-4 inhibitors (DPP-4i) on fractures. In this study, we analyzed the effect of DPP-4i on bone fracture...
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Generalized Eruptive Diabetic Dermopathy: A Rare Clinical Manifestation

Gwak MJ, Shin EJ, Seo JK, Lee JH, Shin MK

  • KMID: 2457701
  • Korean J Dermatol.
  • 2019 Aug;57(7):416-417.
No abstract available.
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Glycosylated Hemoglobin in Subjects Affected by Iron-Deficiency Anemia

Intra J, Limonta G, Cappellini F, Bertona M, Brambilla

Previous studies have suggested that iron-deficiency anemia affects glycosylated hemoglobin (HbA1c) measurements, but the results were contradictory. We conducted a retrospective case-control study to determine the effects of iron deficiency...
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Pharmacotherapy of Diabetes Focused on Stroke

Lyu YS, Kim JH, Kim SY

Cardiovascular disease, including stroke, is one of the major causes of death in diabetes. Numerous studies have long suggested reducing macrovascular complication such as ischemic vascular disease through intensive glycemic...
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Diabetes Mellitus and Cause-Specific Mortality: A Population-Based Study

Li S, Wang J, Zhang B, Li X, Liu Y

BACKGROUND: To investigate whether diabetes contributes to mortality for major types of diseases. METHODS: Six National Health and Nutrition Examination Survey data cycles (1999 to 2000, 2001 to 2002, 2003 to...
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Relationships between the diabetes awareness and clinical indices/nutrient intakes in Korean adults: Based on the 2012–2013 Korea National Health and Nutrition Examination Survey Data

Lee S, Park H, Lee Y, Choi O, Kim J, Gray HL, Song K

BACKGROUND/OBJECTIVES: Diabetes is diagnosed after an average of 10–12 years of diabetic development. Strict glycemic control in diabetic patients promotes the normalization of blood glucose and reduces cardiovascular diseases (CVDs)...
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Intake of Fruits for Diabetics: Why and How Much?

Lee EY

Fruits are universally promoted as healthy. Fruits supply dietary fiber, vitamins, minerals and phytochemicals that function as antioxidants. But many people often have concerns that fruit intake has a negative...
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The effect of alpha-lipoic acid on expression of VCAM-1 in type 2 diabetic rat

Ismawati , Mukhyarjon , Asni E, Romus I

Macrovascular diabetes complications are generally caused by a process called atherosclerosis. Evidences suggest that to initiate atherosclerosis, oxidated low-density lipoprotein (oxLDL) has to promote the expression of adhesion molecule. Several...
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Associations between the HaeIII Single Nucleotide Polymorphism in the SLC2A1 Gene and Diabetic Nephropathy in Korean Patients with Type 2 Diabetes Mellitus

Lee DH, Won GW, Lee YH, Ku EJ, Oh TK, Jeon HJ

BACKGROUND: Diabetic nephropathy (DN) is the most serious microvascular complication of diabetes mellitus and is one of the leading causes of end stage renal failure. In previous studies, the contribution...
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Comparison of Improving Effects for Diabetic Erectile Dysfunction according to the Anti-Glycemic Agents: Phlorizin and Insulin

Park J, Kwon O, Cho SY, Cho MC, Paick JS, Kim SW

PURPOSE: To compare the improving effects of diabetic erectile dysfunction with two anti-glycemic agents; phlorizin and insulin. MATERIALS AND METHODS: Sixty Sprague-Dawley rats were divided into four groups (n=15 in each...
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