Korean J Hematol.
2001 May;36(2):176-179.
Pseudoreticulocytosis in a Case of Myelodysplastic Syndrome
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Pusan National University, Pusan, Korea.
- 2Department of Clinical Pathology, College of Medicine, Pusan National University, Pusan, Korea.
Abstract
- Myelodysplastic syndrome (MDS) is a group of hematopoietic disorders characterized by ineffective hematopoiesis and peripheral cytopenia associated with dysplastic hypercellular marrow. Anemia is a frequent finding and reticulocytes are usually normal or slightly decreased in the patients with MDS. "Pseudoreticulocytosis" is a rare abnormality of patients with MDS. In these patients, the delayed maturation of reticulocytes is revealed and unusual
reticulocytosis occurs with the decreased red cell production. We report a case of MDS characterized by the anemia associated with high reticulocyte count. 'In vitro reticulocyte survival test' showed that the reticulocytosis was a consequence of delayed maturation.