Korean J Clin Microbiol.  2009 Sep;12(3):103-109. 10.5145/KJCM.2009.12.3.103.

Metallo-beta-lactamase Producing Gram-negative Bacilli

• Yong D

• KMID: 1828579
• DOI: http://doi.org/10.5145/KJCM.2009.12.3.103

Abstract

Among gram-negative bacteria, rate of antibiotic resistance has been increasing. As a result, carbapenem is now considered as a last resort of therapeutic regimens for gram-negative bacterial infections. The choice of antibiotics has been impeded by the spread of organisms producing metallo-beta-lactamases (MBL), which can confer resistance to nearly all beta-lactams. MBLs have extremely diverse structures and are carried by various organisms including human pathogens. This review will focus on the classification and current status of MBL reported in Korea.

Keyword

Metallo-beta-lactamase; Gram-negative bacilli

MeSH Terms

Anti-Bacterial Agents
beta-Lactams
Drug Resistance, Microbial
Gram-Negative Bacteria
Gram-Negative Bacterial Infections
Health Resorts
Humans
Korea
Anti-Bacterial Agents
beta-Lactams

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