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Metallo-beta-lactamase Producing Gram-negative Bacilli

Yong D

Among gram-negative bacteria, rate of antibiotic resistance has been increasing. As a result, carbapenem is now considered as a last resort of therapeutic regimens for gram-negative bacterial infections. The choice...
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Interpretation of Antimicrobial Susceptibility Test According to Resistance Mechanism of beta-lactam in Enterobacteriacae

Lee CH

It is important to select appropriate antimicrobials for the treatment of infection according to the results of antimicrobial susceptibility tests (ASTs), yet the clinical isolates are sometimes susceptible to antibiotics...
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Distribution of MIC Values of Various Antibiotics against Extended-spectrum Beta-lactamase (ESBL)-producing Klebsiella pneumoniae

Lee MS, Kwon YM, Kim JM, Yun YS, Yu SM, Pai H

  • KMID: 2082870
  • Korean J Infect Dis.
  • 1997 Mar;29(2):105-112.
BACKGROUND: Extended-spectrum beta-lactamases (ESBLs) confer resistance to extended-spectrum cephalosporin (e.g., cefotaxime, ceftazidime) and aztreonam. But the diversity of ESBLs results in various susceptibility profiles with different beta-lactams. To study the...
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Microbiological Characteristics of Methicillin-resistant Staphylococcus aureus

Yi J, Kim EC

Methicillin-resistant Staphylococcus aureus (MRSA) is a typical pathogen of nosocomial infection, and has recently emerged as an important community-acquired pathogen. MRSA is notorious as a multidrug-resistant organism. Its resistance to...
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Strategies for Interpretive Standards of beta-Lactams Susceptibility Testing and Identification of Extended-Spectrum beta-Lactamases and Carbapenemases in Enterobacteriaceae

Park YJ, Song W

The Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) have recently revised the susceptibility interpretive criteria of oxyimino-beta-lactams and carbapenems for Enterobacteriaceae. According...
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Antimicrobial Susceptibility of Beta-Lactam Antibiotics on Enterococcus

Song SM, Lee JH, Lee NY

  • KMID: 1892796
  • Korean J Clin Microbiol.
  • 1999 Sep;2(2):194-198.
BACKGROUND: Enterococci exhibit intrinsic resistance or high-level minimum inhibitory concentration (MIC) to beta-lactams than other streptococci. This appears to be due to low affinity of penicillin-binding proteins and rarely production...
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Prevalence of TEM- and SHV-type Beta-lactamase gene in Escherichia coli and Klebsiella pneumoniae in Korea

Sohn SH, Lee DJ, Kim CI, Kim JM, Pai HJ

  • KMID: 1548707
  • Korean J Infect Dis.
  • 1997 Jul;29(4):271-276.
BACKGROUND: Resistance to beta-lactams in E. coli is mostly via acquisition of plasmid-mediated beta-lactamase gene. Among the plasmid-mediated beta-lactamases, TEM-1 beta-lactamase is by far the most prevalent among ampicillin-resistant E....
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Plasmid-Mediated Resistance to Extended-Spectrum beta-lactams in Enterobacter cloacae: Report of 4 cases

Lim J, Park YJ, Oh EJ, Kim BK, Shim SI

  • KMID: 2248576
  • Korean J Infect Dis.
  • 1998 Jun;30(3):284-288.
BACKGROUND: Enterobacter species are frequent nosocomial pathogens and the proportion of beta-lactam resistant strains are on the increase. Extended spectrum beta-lactamases(ESBLs) were mainly investigated in Klebsiella pneumoniae and Escherichia coli...
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Evaluation of Changed Antibiotics in Case of Positive Antibiotics Skin Test

  • KMID: 2090211
  • Korean J Asthma Allergy Clin Immunol.
  • 2011 Mar;31(1):48-54.
BACKGROUND: Antibiotics skin test (AST) is routinely performed to examine hypersensitivity in clinical practice. However, it is difficult to select antibiotics in case of positive AST because of poor validation...
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Synergistic Anti-bacterial Effects of Phellinus baumii Ethyl Acetate Extracts and beta-Lactam Antimicrobial Agents Against Methicillin-Resistant Staphylococcus aureus

Hong SB, Rhee MH, Yun BS, Lim YH, Song HG, Shin KS

BACKGROUND: The development of new drugs or alternative therapies effective against methicillin-resistant Staphylococcus aureus (MRSA) is of great importance, and various natural anti-MRSA products are good candidates for combination therapies....
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Clinical Efficacy of Ertapenem for Recurrent Cystitis Caused by Multidrug-Resistant Extended-Spectrum beta-Lactamase-Producing Escherichia coli in Female Outpatients

Song S, Kim C, Lim D

PURPOSE: To evaluate the clinical outcomes of ertapenem administered as an outpatient parenteral antibiotic therapy for intractable cystitis caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. MATERIALS AND METHODS: We retrospectively reviewed...
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Prevalence of Metallo-beta-lactamases in Imipenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii

Ryoo NH, Ha JS, Jeon DS, Kim JR

BACKGROUND: Metallo-beta-lactamases (MBLs) have been reported in gram negative bacilli and are becoming increasingly important clinically because the enzymes hydrolyse almost all beta-lactams, including carbapenems. Thus, the present study was...
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Correlation Between Staphylococcal Cassette Chromosome mec Type and Coagulase Serotype of Methicillin-Resistant Staphylococcus aureus

Cha EK, Chang KS, Hwang SM

Staphylococcal cassette chromosome mec (SCCmec) type and coagulase serotype are important epidemiologic factors in methicillin-resistant Staphylococcus aureus (MRSA). To investigate correlation between SCCmec type and coagulase serotype of MRSA, we...
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Characteristics of Extended-spectrum Beta-lactam Hydrolyzing Activity of Klebsiella pneumoniae and Escherichia coli Strains Isolated from Clinical Specimens

Chong Y, Lee K, Okamoto R, Inoue M

  • KMID: 1548825
  • Korean J Infect Dis.
  • 1997 Nov;29(6):477-486.
BACKGROUND: Increase in Escherichia coli and Klebsiella pneumoniae isolates with extended- spectrum beta-lactamase (ESBL) have been noted recently in Korea. Current NCCLS disk diffusion test is not sensitive to detect...
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Two Cases of Ingestion of Rhus Chicken Causing Acute Generalized Exanthematous Pustulosis

Kim MS, Kim DJ, Na CH, Shin BS

  • KMID: 2245941
  • Korean J Dermatol.
  • 2015 Jul;53(6):473-477.
Rhus chicken is a common health food in Korea and is used as an herbal medicine to cure gastrointestinal diseases such as indigestion, loose stool, and peptic ulcers. Unfortunately, systemic...
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Update on the diagnosis of drug allergy

Cho YJ

  • KMID: 1490320
  • Korean J Med.
  • 2009 Mar;76(3):282-290.
Hypersensitivity reactions to drugs are classified as immediate or nonimmediate reactions depending on the basis of time of appearance of reactions. Clinical and immunological studies suggest that immediate reaction is...
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A Case of Meropenem-Resistant Ochrobactrum anthropi Bacteremia

Kim GM, Jin SJ, Yoo JS, Kim CO, Choi JY, Kim JM, Song YG

Ochrobactrum anthropi is an oxidase-producing, non-lactose-fermenting, gram-negative bacillus that is frequently isolated from the environment including sinks, baths, soil, and hospital water sources. Recently O. anthropi have been reported as...
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Combination Effects of Various Beta-Lactam Antibiotics with Vancomycin or Teicoplanin against Staphylococcus aureus with Reduced Susceptibility to Vancomycin

Rheem IS, Kim JM, Park JW, Kim YH, Na HK, Kim MJ, Kim JW

  • KMID: 1889925
  • Korean J Lab Med.
  • 2002 Jun;22(3):169-180.
BACKGROUND: Combination effects of various beta-lactam antibiotics with vancomycin or teicoplanin against methicillin-resistant Staphylococcus aureus (MRSA) that were detected as pos-sible hetero-vancomycin resistant Staphylococcus aureus (hetero-VRSA) by the Mu-3 agar...
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In Vitro Activities of Cefminox against Enterobacteriaceae Species, Haemophilus influenzae, and Methicillin-Susceptible Staphylococcus aureus

Chong Y, Lee K, Shin HB, Chung JL

  • KMID: 2248613
  • Korean J Infect Dis.
  • 1998 Oct;30(5):450-459.
BACKGROUND: Recent clinical isolates of bacteria often produce various beta-lactamases, for example, extended spectrum beta-lactamase (ESBL) by some species of Enterobacteriaceae, TEM beta-lactamase by Haemophilus influenzae, and penicillinase by methicillin-susceptible...
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Antimicrobial Susceptibility of Inducible AmpC beta-lactamase-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens: a Korean Survey

Park YJ, Lee S, Yong D, Lee K, Kim BK, Kang CS

  • KMID: 1889897
  • Korean J Lab Med.
  • 2003 Aug;23(4):251-257.
BACKGROUND: Antimicrobial resistance to third-generation cephalosporins in gram-negative bacteria, especially Enterobacter, Citrobacter, and Serratia spp., is increasing. The resistance mechanism of these organisms are hyperproduction of AmpC beta-lactamase and plasmid-mediated...
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