Infect Chemother.  2009 Feb;41(1):62-64. 10.3947/ic.2009.41.1.62.

A Case of Meropenem-Resistant Ochrobactrum anthropi Bacteremia

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. imfell@yuhs.ac

Abstract

Ochrobactrum anthropi is an oxidase-producing, non-lactose-fermenting, gram-negative bacillus that is frequently isolated from the environment including sinks, baths, soil, and hospital water sources. Recently O. anthropi have been reported as an emerging opportunistic pathogen in immunocompromised patients, particularly in those with indwelling venous catheters. Most O. anthropi were highly resistant to beta-lactam antibiotics except carbapenem. We report a case of O. anthropi bacteremia with an unusual pattern of antibiotic resistance compared to previous reports. A 47-year-old woman undergoing camptobell/cisplatin chemotherapy via indwelling venous catheter (chemoport) for stage IV ovarian cancer, had septicemia due to O. anthropi of unknown origin. The isolates were resistant to all beta-lactams and meropenem and susceptible to aminoglycoside, ciprofloxacin, and trimethoprim-sulfamethoxazole. She recovered from sepsis with combination treatment with imipenem and ciprofloxacin for 3 weeks.

Keyword

Ochrobactrum anthropi; Bacteremia; Meropenem; Resistant

MeSH Terms

Anti-Bacterial Agents
Bacillus
Bacteremia
Baths
beta-Lactams
Catheters
Ciprofloxacin
Drug Resistance, Microbial
Female
Humans
Imipenem
Immunocompromised Host
Middle Aged
Ochrobactrum
Ochrobactrum anthropi
Ovarian Neoplasms
Sepsis
Soil
Thienamycins
Trimethoprim, Sulfamethoxazole Drug Combination
Anti-Bacterial Agents
Ciprofloxacin
Imipenem
Soil
Thienamycins
beta-Lactams
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