Yeungnam Univ J Med.  2010 Jun;27(1):8-17. 10.12701/yujm.2010.27.1.8.

Interpretation of Antimicrobial Susceptibility Test According to Resistance Mechanism of beta-lactam in Enterobacteriacae

• Lee CH

• KMID: 1462706
• DOI: http://doi.org/10.12701/yujm.2010.27.1.8

Abstract

It is important to select appropriate antimicrobials for the treatment of infection according to the results of antimicrobial susceptibility tests (ASTs), yet the clinical isolates are sometimes susceptible to antibiotics that are clinically ineffective or this is due to technical error of the ASTs. So, interpretive reading of ASTs is needed and especially for the beta-lactams for treating Enterobacteriacae. This review describes the interpretive reading of ASTs according to natural antimicrobial resistance and the mechanisms of mechanisms, with giving special attention to the antibiotics phenotypes for Enterobacteriacae. Further, as all the diffent tissues have a different antimicrobial concentration for identical antimicrobials, more information is needed on the antimicrobial tissue distribution for the appropriate treatment of infection. (ED note: I hope you send me the paper.)

Keyword

Antimicrobial Susceptibility Test; beta-lactam

MeSH Terms

Anti-Bacterial Agents
beta-Lactams
Phenotype
Tissue Distribution
Anti-Bacterial Agents
beta-Lactams