Korean J Intern Med.
2013 Nov;28(6):724-727. 10.3904/kjim.2013.28.6.724.
Postinfectious Guillain-Barre syndrome in a patient with methimazole-induced agranulocytosis
- Affiliations
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- 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. swkimmd@skku.edu
- 2Division of Endocrinology and Metabolism, Department of Internal Medicine, Dong-A Medical Center, Dong-A University College of Medicine, Busan, Korea.
- KMID: 1780135
- DOI: http://doi.org/10.3904/kjim.2013.28.6.724
Abstract
- Both Graves disease and Guillain-Barre syndrome (GBS) are autoimmune disorders caused by impaired self-tolerance mechanisms and triggered by interactions between genetic and environmental factors. GBS in patients who suffer from other autoimmune diseases is rarely reported, and the development of postinfectious GBS in a patient with Graves disease has not been previously reported in the literature. Herein, we report a patient with Graves disease who developed postinfectious GBS during a course of methimazole-induced agranulocytosis.
MeSH Terms
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Agranulocytosis/*chemically induced/diagnosis/therapy
Antithyroid Agents/*adverse effects
Female
Graves Disease/diagnosis/*drug therapy
Guillain-Barre Syndrome/diagnosis/*etiology/therapy
Humans
Immunoglobulins, Intravenous/therapeutic use
Methimazole/*adverse effects
Middle Aged
Opportunistic Infections/diagnosis/*etiology/therapy
Thyroidectomy
Treatment Outcome
Antithyroid Agents
Immunoglobulins, Intravenous
Methimazole
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