J Korean Soc Pediatr Endocrinol.
2004 Jun;9(1):81-85.
A Case of Antithyroid Drug-Induced Agranulocytosis Treated with Granulocyte Colony-Stimulating Factor (G-CSF) and Methylprednisolone
Abstract
- Although rare, agranulocytosis is the most serious, potentially fatal side effect of antithyroid drug. We experienced a 13-year-old girl who developed methimazole-induced agranulocytosis at 1 month after the initiation of treatment. Her granulocyte count recovered after discontinuation of methimazole and treatment with broad spectrum-antibiotics, G-CSF, and methylprednisolone. After recovery from agranulocytosis she was treated with radioiodine ablation therapy. Early detection and proper management of antithyroid drug-induced agranulocytosis is very important.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Granulocyte-Colony Stimulating Factor(G-CSF) Treatment of Clozapine-induced Agranulocytosis
- Two cases of congenital agranulocytosis treated with recombinant human granulocyte colony-stimulating factor
- Allopurinol-induced agranulocytosis in a patient on peritoneal dialysis
- A Case of Transient Granulocytopenia during Treatment of a Patient with Graves' Disease and Type 1 Diabetes Mellitus - Differential Diagnosis from Agranulocytosis by a Single Injection of G-CSF
- A case of PTU(propylthiouracil)-induced agranulocytosis in Graves' disease: additional cases of antithyroid drug-induced agranulocytosis in Yonsei University Hospital last 10 years
