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Reversal of Olfactory Disturbance in Allergic Rhinitis Related to OMP Suppression by Intranasal Budesonide Treatment

Jung AY, Kim YH

PURPOSE: We evaluated the severity of olfactory disturbance (OD) in the murine model of allergic rhinitis (AR) and local allergic rhinitis (LAR) in mice. We also investigated the therapeutic effect...
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Case of Raynaud Syndrome after the Use of Methimazole

Kim Y, Tag HS, Kim GT, Lee SG, Park EK, Park JH, Kweon SM, Yang SI, Kim JH

Raynaud syndrome is a medical condition that causes pain, numbness, and changes in skin color at the distal extremities. Raynaud syndrome can be subdivided into primary Raynaud's and secondary Raynaud's....
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Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study

Kwon H, Jung JH, Han KD, Park YG, Cho JH, Lee DY, Han JM, Park SE, Rhee EJ, Lee WY

BACKGROUND: The incidence of thyroid nodules has increased worldwide in recent years. Thyroid dysfunction is a potential risk factor for hypercholesterolemia, cardiovascular disease, osteoporosis, arrhythmia, and neuropsychiatric disease. This study...
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A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection

Hong SE, Choo JW, Lim SK, Lee SJ, Park JW, Kim SE, Kim JH, Park CK

Concurrent presentation of acute hepatitis A virus (HAV) infection and Graves' disease has not been reported in literature worldwide. Although there is no well-established mechanism that explains the induction of...
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Thyroid dysfunction during pregnancy

Yim CH

Thyroid dysfunction during pregnancy can result in serious complications for both the mother and infant. However, these complications can be prevented by the optimal treatment of overt maternal thyroid dysfunction....
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RE: Novel Application of Quantitative Single-Photon Emission Computed Tomography/Computed Tomography to Predict Early Response to Methimazole in Graves' Disease

Zhang W, Huang ZQ, Lin WL, Yang SH

No abstract available.
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Methimazole-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in the Peripheral Nerves

Kang MI, Kim D

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis has been reported in Graves' disease patients treated with antithyroid drugs (ATDs), especially propylthiouracil. ATD-induced ANCA-associated vasculitis usually involved the kidneys followed by the respiratory...
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Clinical Features of Serious Adverse Drug Reactions in a Tertiary Care Hospital in Korea

Seo Y, Han Y, Kim SH, Son ES, Sim DW, Park KH, Park JW

BACKGROUND/AIMS: Several studies have reported on the clinical aspects of adverse drug reactions (ADRs). To date, no study has evaluated serious adverse drug reactions (SADRs) in Korea. The current study...
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Cytoplasmic Anti-Neutrophil Cytoplasmic Antibody Positive Diffuse Alveolar Hemorrhage Associated with Methimazole

Ryu HS, Park JH, Sheen SS, Kim TH, Han SD, Jung JY, Suh CH, Hwang SC

Diffuse alveolar hemorrhage (DAH) is a life-threatening condition associated with many disorders. Here, we report a case of 59-year-old female who had diffuse alveolar hemorrhage associated with methimazole. She had...
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Novel Application of Quantitative Single-Photon Emission Computed Tomography/Computed Tomography to Predict Early Response to Methimazole in Graves' Disease

Kim HJ, Bang JI, Kim JY, Moon JH, So Y, Lee WW

OBJECTIVE: Since Graves' disease (GD) is resistant to antithyroid drugs (ATDs), an accurate quantitative thyroid function measurement is required for the prediction of early responses to ATD. Quantitative parameters derived...
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Severe chest pain with mid-ventricular obstruction in a patient with hyperthyroidism

Nam JH, Son JW, Hong GR

Mid-ventricular obstruction (MVO) rarely occurs in patients without hypertrophic cardiomyopathy. Increased cardiac contractility may play an important role in causing MVO. We experienced a case of severe chest pain and...
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Free Thyroxine, Anti-Thyroid Stimulating Hormone Receptor Antibody Titers, and Absence of Goiter Were Associated with Responsiveness to Methimazole in Patients with New Onset Graves' Disease

Choi HS, Yoo WS

BACKGROUND: Anti-thyroid drug therapy is considered a treatment of choice for Graves' disease; however, treatment response varies among individuals. Although several studies have reported risk factors for relapse after initial...
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Sweet's Syndrome Associated with Graves' Disease

Yong HJ, Kang MI, Kim D

Sweet's syndrome, or acute febrile neutrophilic dermatosis, occurs in association with autoimmune diseases such as Hashimoto's thyroiditis but is rare in Graves' disease, in which all cases are induced by...
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Cholestyramine Use for Rapid Reversion to Euthyroid States in Patients with Thyrotoxicosis

Ha J, Jo K, Kang B, Kim MH, Lim DJ

Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. The use of CS added to conventional antithyroid drugs to control thyrotoxicosis...
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Abnormal Nocturnal Sensation of Hands in the Patient with Hyperthyroidism

Kim DE, Shin DS, Lee SC, Park HK, Yang KI

The symptoms of restless legs syndrome usually involve legs, but can extend to other body parts. However, isolated body parts other than the leg are rarely involved. A 36-year-old woman...
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Dilated cardiomyopathy with Graves disease in a young child

Choi YJ, Jang JH, Park SH, Oh JH, Koh DK

Graves disease (GD) can lead to complications such as cardiac arrhythmia and heart failure. Although dilated cardiomyopathy (DCMP) has been occasionally reported in adults with GD, it is rare in...
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Predictive factors for early response to methimazole in children and adolescents with Graves disease: a single-institute study between 1993 and 2013

Hwang SM, Kim MS, Lee DY

PURPOSE: We aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD). METHODS: Our study included 44 pediatric patients who were diagnosed...
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A Case of Methimazole-Resistant Severe Graves' Disease: Dramatic Response to Cholestyramine

Chae SB, Kim ES, Lee YI, Min BR

A 22-year-old woman with severe Graves' disease was referred from a local clinic because of her refractory hyperthyroidism. She presented with exophthalmos, diffuse goiter, and tachycardia. She was treated with...
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Anti-tuberculosis Treatment-Induced Insulin Autoimmune Syndrome

Han JS, Moon HJ, Kim JS, Kim HI, Kim CH, Kim MJ

Insulin autoimmune syndrome, a rare cause of endogenous hyperinsulinemic hypoglycemia, is characterized by insulin autoantibody, hyperinsulinemia and fasting hypoglycemia. It is well known that drugs containing a sulfhydryl group such...
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A Case of Graves' Disease Occurring after Subacute Thyroiditis

Seo HM, Beom JW, Kim SH, You SY, Kim JY, Koh GP, Lee SA

Graves' disease following subacute thyroiditis is uncommon. Some patients in these cases showed positive for thyroid antibody only transiently in the resolving phase. However, Graves' disease can rarely be caused...
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