- Agranulocytosis due to secondary exposure to antithyroid drugs in a relapsed Graves' disease patient
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Jeong GH, Kim SK, Myung DS, Chung JO, Cho DH, Chung DJ, Chung MY
- KMID: 2258791
- Korean J Med.
- 2008 Sep;75(3):362-366.
Antithyroid drugs are the most common treatment modality for Graves' disease and are used for the treatment of relapsed Graves' disease in Korea. Agranulocytosis is a rare and severe complication... -
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- The treatment of Graves' disease in children and adolescents
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Lee HS, Hwang JS
- KMID: 2134078
- Ann Pediatr Endocrinol Metab.
- 2014 Sep;19(3):122-126.
- doi: 10.6065/apem.2014.19.3.122
Graves' disease (GD) accounts for 10%-15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted. An average... -
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- Medical Treatment of Graves' Disease
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Chung HK
- KMID: 2465059
- Int J Thyroidol.
- 2019 Nov;12(2):79-84.
- doi: 10.11106/ijt.2019.12.2.79
Among the three treatment modalities of Graves' disease which include antithyroid drug (ATD), radioactive iodine and surgery, the ATD is most commonly preferred in Korea due to ease of use... -
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- Factors affecting drug-induced liver injury: antithyroid drugs as instances
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Heidari R, Niknahad H, Jamshidzadeh A, Abdoli N
- KMID: 2069759
- Clin Mol Hepatol.
- 2014 Sep;20(3):237-248.
- doi: 10.3350/cmh.2014.20.3.237
Methimazole and propylthiouracil have been used in the management of hyperthyroidism for more than half a century. However, hepatotoxicity is one of the most deleterious side effects associated with these... -
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- The Change of Thyroid Hormone by Short-term Antithyroid Drug Treatment for Preoperative Euthyroidism in TSH-secreting Pituitary Adenoma
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Lee MH, Park JH
- KMID: 2200566
- J Korean Soc Endocrinol.
- 2005 Jun;20(3):261-267.
- doi: 10.3803/jkes.2005.20.3.261
Preoperative euthyroidism is needed to minimize the risk of intraoperative and postoperative complications, such as thyroid storm by surgery. Antithyroid drugs or steroid hormones are commonly used in primary hyperthyroidism... -
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- A Case of Acute Supraglottitis Following Anti-Thyroid Drug-Induced Agranulocytosis
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Lee JJ, Kim DY, Jang JY
- KMID: 2470497
- J Korean Soc Laryngol Phoniatr Logoped.
- 2019 Dec;30(2):128-131.
- doi: 10.22469/jkslp.2019.30.2.128
Acute supraglottitis is characterized by an inflammation and edema of the supraglottic region and a potential life-threatening condition because of its risk for sudden upper airway compromise. Prompt diagnosis, administration... -
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- Postoperative Thyroid Storm
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Park KS, Kim MJ, Kown BY
- KMID: 2116506
- Korean J Anesthesiol.
- 1988 Jun;21(3):509-512.
- doi: 10.4097/kjae.1988.21.3.509
Thyrold storm, when related to surgery, usually develops within 6~18 hours postoperatively, with symptoms and signs of pyrexia, marked tachycardia, susceptability to severe hypotension, and restlessness. There are a few... -
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- The Recurrence Rate of Graves' Disease among Patients with Subclinical Thyrotoxicosis after Initial Remission with Antithyroid Agents
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Shim MS, Nam SM, Yoo JS, Kim HK, Lee SJ, Lee MY
- KMID: 2396810
- Int J Thyroidol.
- 2017 Nov;10(2):77-81.
- doi: 10.11106/ijt.2017.10.2.77
BACKGROUND AND OBJECTIVES: The recurrence rate of patients with Graves' disease (GD) is estimated to be 50-55% after withdrawal of antithyroid drug therapy, and relapse is frequent in the first... -
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- Adequate Duration of Medical Therapy for Koreans with Graves' Disease
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Lee HS, Lee DH, Chung HS, Lee JW, Kim JE, Shin SS, Chung YS, Lee KW, Kim HM
- KMID: 2200124
- J Korean Soc Endocrinol.
- 2003 Feb;18(1):24-31.
BACKGROUND: Graves' disease is an organ specific autoimmune disease. Three kinds of therapeutic modalities(antithyroid drugs, ablation with radioactive iodine and subtotal thyroidectomy) are frequently performed for the management of this... -
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- Treatment of relapsed hyperthyroidism
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Chung JH
- KMID: 2409044
- J Korean Med Assoc.
- 2018 Apr;61(4):248-252.
- doi: 10.5124/jkma.2018.61.4.248
Graves disease is the most common disease that causes hyperthyroidism. It is an autoimmune disease characterized by the overproduction of thyroid hormones due to continuous stimulation of the thyroid gland... -
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- Methimazole-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in the Peripheral Nerves
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Kang MI, Kim D
- KMID: 2448990
- Int J Thyroidol.
- 2018 Nov;11(2):176-181.
- doi: 10.11106/ijt.2018.11.2.176
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis has been reported in Graves' disease patients treated with antithyroid drugs (ATDs), especially propylthiouracil. ATD-induced ANCA-associated vasculitis usually involved the kidneys followed by the respiratory... -
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- Effects of short-term potassium iodide treatment for thyrotoxicosis due to Graves disease in children and adolescents
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Jeong KU, Lee HS, Hwang JS
- KMID: 1769352
- Ann Pediatr Endocrinol Metab.
- 2014 Dec;19(4):197-201.
- doi: 10.6065/apem.2014.19.4.197
PURPOSE: Graves disease is the most common cause of hyperthyroidism in children. Inorganic iodide has been used in combination with antithyroid drugs for more effective normalization of thyroid hormones in... -
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- A Case Report of Methimazole-Induced Acute Liver Failure Successfully Treated with Liver Transplantation
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Jeon SJ, Kim TY, Lee SH, Kang JS, Choi GH, Lee SG, Hwang HS
- KMID: 2263459
- Korean J Med.
- 2012 Sep;83(3):363-368.
Antithyroid drugs inhibit the synthesis and excretion of thyroid hormone from the thyroid gland. Propylthiouracil (PTU) and methimazole are well known as antithyroid drugs. In 2011, the American Thyroid Association... -
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- A Case of Agranulocytosis and Soft Tissue Abscess after Increasing Methimazole Dose in a Patient with Graves Disease under Long-term Mainternance Therapy
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Park SY, Chun SW, Kim YJ, Kim SJ
- KMID: 2012972
- J Korean Thyroid Assoc.
- 2011 May;4(1):54-57.
Antithyroid drugs (ATD) has been widely used to treat Graves' disease. However agranulocytosis, a serious fatal complication of ATD treatment, occurs in about 0.5 percent. The symptoms may mimic viral... -
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- Cholestyramine Use for Rapid Reversion to Euthyroid States in Patients with Thyrotoxicosis
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Ha J, Jo K, Kang B, Kim MH, Lim DJ
- KMID: 2352989
- Endocrinol Metab.
- 2016 Sep;31(3):476-479.
- doi: 10.3803/EnM.2016.31.3.476
Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. The use of CS added to conventional antithyroid drugs to control thyrotoxicosis... -
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- Analysis of the markers related with relapse after withdrawal of antithyroid drug in patients with Graves' disease
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Kim KW, Park YJ, Lee YJ, Lee EJ, Lee EK, Park MH, Park DJ, Cho BY
- KMID: 2256414
- Korean J Med.
- 2007 May;72(5):522-528.
BACKGROUND: Graves' disease is an organ-specific autoimmune disease that is characterized by thyrotoxicosis, and this is caused by TSH receptor stimulating autoantibody. Antithyroid drugs have been a mainstay of treatment... -
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- Changes in Thyrotropin Receptor Blocking Antibody after Antithyroid drug Administration to Patients with Atrophic Autoimmune Thyroiditis (Primary Myxedema)
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Kim SY, Cho BY, Lee HK, Chung JH, Koh CS, Shin CS, Kim WB
- KMID: 2461568
- J Korean Soc Endocrinol.
- 1994 Sep;10(3):229-241.
It is well Known that antithyroid drug treatment of Graves' disease suppresses excessive thyroid hormone synthesis and causes a parallel decrease in serum thyroid autoantibody levels including thyroid stimulating antibodies(TSAb)... -
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- Changes of Intercellular Adhesion Molecule-1 (ICAM-1) in Sera of Patients with Graves' Diease before and after Treatment with Antithyroid Drug
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Song CU, Ahn BS, Jeon JS, Lee JH, Ahn MA, Shong MH, Ro HK
- KMID: 2461542
- J Korean Soc Endocrinol.
- 1995 Mar;10(1):45-51.
Intercellular Adhesion Molecule-1(ICAM-1) plays an important role in a variety of inflammatory and immune-mediated mechanisms, including lymphocyte recruitment and targeting, antigen presentation and recognition, and lymphocyte cytotoxicity.In order to study... -
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- A Case of Transient Granulocytopenia during Treatment of a Patient with Graves' Disease and Type 1 Diabetes Mellitus - Differential Diagnosis from Agranulocytosis by a Single Injection of G-CSF
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Park JK, Seong JH, Lee J, Chu SN, Jeong H, Kim YL, Park SW, Cho YW, Lee SJ
- KMID: 2199946
- J Korean Soc Endocrinol.
- 2002 Apr;17(2):280-285.
Granulocytopenia, which can be seen in patients with Graves' disease during treatment with antithyroid agents, could be a self resolving transient episode or can imply the beginning of life threatening... -
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- Retrospects of Twentieth-Century and Prospects toward Twenty First-Century in Thyroid Surgery
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Kim SH
- KMID: 2376210
- Korean J Endocr Surg.
- 2001 Apr;1(1):6-13.
- doi: 10.16956/kjes.2001.1.1.6
Though the first well-documented thyroidectomy was performed in 1595, Kocher at Bern, Switzerland can be called “Father of thyroid surgery†with his outstanding contributions to the understanding of thyroid disease... -
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