J Korean Acad Periodontol.  2009 Jun;39(2):129-138. 10.5051/jkape.2009.39.2.129.

Clinical study of guided bone regeneration of extracted socket with PLA/PGA membrane and silk fibroin membrane

• Hwang WJ
• Jeong SN
• Kim YS
• Pi SH
• You HK
• Chung CP
• Shin HS

• KMID: 1733730
• DOI: http://doi.org/10.5051/jkape.2009.39.2.129

Abstract

PURPOSE: This study was designed to compare the bond regeneratiom effects of treatment using silk fibroin membrane ( Nanogide-S (R)) resorbable barrier with control group treated by polyactic acid / polylacticglycolic acid membrane(Biomesh (R) )
METHODS
44 severe bone loss on extraction socket from 44 patients were used in this study. In experimental group 22 sites of them were treated by silk fibrin membrane as and the other 22 sites were treated by polyactic acid/ polylacticglycolic acid membrane as a control group. Clinical parameters including recovered bone width, length and radiographic parameter of vertical length were evlauated at base line and 3 months after surgery.
RESULTS
1) Severe bone width, length was significantlly decreased in two group. 2) Bone width, length was significantlly decreased in two group. 3) Decreased bone width, length and radiographic examination differences between group.
CONCLUSIONS
On the basis of these results, silk fibrin resorbable membrane has similar bone regeneration ability to polyactic acid / polylacticglycolic acid membrane in guided bone regeneration for severe bone loss defect on extraction socket.

Keyword

fibroin; polylactic acid-polyglycolic acid copolymer; regeneration

MeSH Terms

Bone Regeneration
Fibrin
Fibroins
Humans
Lactic Acid
Membranes
Polyglycolic Acid
Regeneration
Silk
Fibrin
Fibroins
Lactic Acid
Polyglycolic Acid
Silk

Figure

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  Figure 1 Comparison of mesio-distal width of bone defects according to treatment period(Mean±S.D, mm).

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  Figure 2 Comparison of bucco-lingual width of bone defects according to treatment period(Mean±S.D, mm).

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  Figure 3 Comparison of radiographic depth of bone defects according to treatment period(Mean±S.D,mm).

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