Ewha Med J.  2013 Dec;36(Suppl):S1-S4. 10.12771/emj.2013.36.S.S1.

Two Cases of Dengue Fever Due to Dengue Virus-1 Developed in a Family

• Chang JY
• Chung UK
• Yoon SH
• Kim KH
• Choi HJ

• KMID: 1726725
• DOI: http://doi.org/10.12771/emj.2013.36.S.S1

Abstract

We report two cases of dengue fever due to DENV-1 in the family members who returned from Manila, Philippines. Case 1: A 41-year-old female visited the clinic with a general weakness. She had a fever for 5 days. When she came back to Korea, her fever had subsided. The immunoglobulin M (IgM)-capture enzyme-linked immunosorbent assay for dengue virus was positive. Case 2: A 11-year-old female was admitted to the pediatric department after reporting symptoms of fever and abdominal pain upon returning from the Philippines. The RT-PCR result for DENV-1 was positive in blood, but IgM came out negative. Dengue fever should be suspected for those who have returned from an endemic area with reports of febrile illness and rash, particularly if thrombocytopenia, leukopenia, elevated serum aminotransferase are present. Using RT-PCR and serological test, the precise diagnosis should be made and proper management should be given to prevent secondary complications.

Keyword

Clinical manifestation; Dengue fever; Dengue virus serotype; Diagnosis

MeSH Terms

Abdominal Pain
Adult
Child
Dengue Virus
Dengue*
Diagnosis
Enzyme-Linked Immunosorbent Assay
Exanthema
Female
Fever
Humans
Immunoglobulin M
Korea
Leukopenia
Philippines
Serologic Tests
Thrombocytopenia
Immunoglobulin M

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