J Korean Acad Periodontol.  2005 Sep;35(3):591-596. 10.5051/jkape.2005.35.3.591.

Amlodipine-induced gingival overgrowth around dental implants

Affiliations
  • 1Department of Dentistry, College of Medicine, Inha University, Korea. kik@inha.ac.kr
  • 2Department of Periodontology, College of Dentistry, Kangnung National University, Korea.

Abstract

Amlodipine, nifedipine, and felodipine are calcium channel blocking agents, which are cause of unwanted gingival overgrowth around natural teeth. Many studies has been performed about this unwanted effects. However, the exact etiology remains uncertain.Few reports and investigations can be found in the literature on drug-induced gingival overgrowth around dental implants. The present case reports that amlodipine-induced gingival overgrowth occurred in peri-implant sites, confirms clinical and histological features in hyperplastic peri-implant tissues. Clinical and histological features of amlodipine-induced gingival overgrowth around dental implants were similar to that of tissue around natural teeth.

Keyword

Calcium channel blocking agents; amlodipine; Gingival hyperplasia; Peri-implant tissue
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