Korean J Med.  2003 Jun;64(6):700-702.

A case of gingival hyperplasia caused by amlodipine

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, College of Medicine, Hallym University, Seoul, Korea. yis21@unitel.co.kr

Abstract

Calcium channel blockers are used to treat hypertension. Unwanted side effects associated with calcium channel blockers are facial flushing, headache, palpitation, dizziness, peripheral edema, constipation, indigestion, nausea, gingival hyperplasia, facial edema and fatigue. Gingival hyperplasia is a rare adverse effect of calcium channel blockers. Calcium channel blockers are known to contribute to gingival hyperplasia. Among all calcium-channel blockers, the prevalence of gingival hyperplasia is highest with nifedipine. Amlodipine is used extensively for the management of hypertension. Several cases have been published since 1994 indicating that amlodipine may also promote gingival hyperplasia. Amlodpine-induced gingival hyperplasia has not reported yet in Korea. We report a case of gingival hyperplasia caused by amlodipine.

Keyword

Amlodipine; Gingival hyperplasia; Calcium channel blockers

MeSH Terms

Amlodipine*
Calcium Channel Blockers
Constipation
Dizziness
Dyspepsia
Edema
Fatigue
Flushing
Gingival Hyperplasia*
Headache
Hypertension
Korea
Nausea
Nifedipine
Prevalence
Amlodipine
Calcium Channel Blockers
Nifedipine
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