J Korean Epilepsy Soc.
2004 Dec;8(2):103-107.
Epilepsy and Oxidative Stress
- Affiliations
-
- 1Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea. wskim@chungbuk.ac.kr
Abstract
- Epilepsy is arising from many molecular and biochemical events. In the underlying mechanisms of epilepsy, oxidative stress plays an important role in seizure-induced brain damage and neuronal death. Also epileptic seizures are noted in mitochondrial diseases with problems in oxidative phosphorylation. So oxidative stress is an important emerging cause of seizure-induced neuronal death as well as a result of epileptic seizure event.