Korean J Hepatol.
1997 Mar;3(1):70-77.
Spontaneous Retroperitoneal Hematoma due to Liver Cirrhosis: A Case Report
Abstract
- Spontaneous retroperitoneal hemorrhage due to liver cirhosis associated
with impaired coagulopathy is very rare disease. Spontaneous retroperitoneal
hemorrhage has been recorded as having originated from many retroperitoneal
organs and blood vessels, and it may be due to local disease and/or systemic factors.
In the majority of patients the bleeding arose from the kidney or adrenal gland.
Among the systemic causes of spontaneous retroperitoneal hemorrhage are
anticoagulation therapy and chronic hemodialysis during the course of which
hemorrhagic complications may occur at many site, including the retroperitoneal space.
Blood dyscrasias have been a rare cause of spontaneous retroperitoneal hemorrhage.
Conditions reported have been included hemophilia, leukemia, polycythemia and sickle
cell trait. Virtually every hemostatic function may be impaired in patients with
severe hepatic disease as the result of failure of both the biosynthetic and clearence
function of the liver, thrombocytopenia, platelet dysfunction, intravascular
coagulation and fibrinogenolysis, and the effects of products of fibrinogen catabolism
on the coagulation mechanism. We are reporting a case of spontaneous retroperitoneal
hematoma in a patient with alcoholic liver cirrhosis with brief review of literature.