Korean J Hepatol.  1997 Mar;3(1):70-77.

Spontaneous Retroperitoneal Hematoma due to Liver Cirrhosis: A Case Report

Abstract

Spontaneous retroperitoneal hemorrhage due to liver cirhosis associated with impaired coagulopathy is very rare disease. Spontaneous retroperitoneal hemorrhage has been recorded as having originated from many retroperitoneal organs and blood vessels, and it may be due to local disease and/or systemic factors. In the majority of patients the bleeding arose from the kidney or adrenal gland. Among the systemic causes of spontaneous retroperitoneal hemorrhage are anticoagulation therapy and chronic hemodialysis during the course of which hemorrhagic complications may occur at many site, including the retroperitoneal space. Blood dyscrasias have been a rare cause of spontaneous retroperitoneal hemorrhage. Conditions reported have been included hemophilia, leukemia, polycythemia and sickle cell trait. Virtually every hemostatic function may be impaired in patients with severe hepatic disease as the result of failure of both the biosynthetic and clearence function of the liver, thrombocytopenia, platelet dysfunction, intravascular coagulation and fibrinogenolysis, and the effects of products of fibrinogen catabolism on the coagulation mechanism. We are reporting a case of spontaneous retroperitoneal hematoma in a patient with alcoholic liver cirrhosis with brief review of literature.

Keyword

Spontaneous retroperitoneal hematoma; Liver cirrhosis; Coagulopathy

MeSH Terms

Adrenal Glands
Blood Platelets
Blood Vessels
Fibrinogen
Hematoma*
Hemophilia A
Hemorrhage
Humans
Kidney
Leukemia
Liver Cirrhosis*
Liver Cirrhosis, Alcoholic
Liver*
Metabolism
Polycythemia
Rare Diseases
Renal Dialysis
Retroperitoneal Space
Sickle Cell Trait
Thrombocytopenia
Fibrinogen
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